VOCLOSPORIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C63H111N11O12
Molecular Weight	1214.6219
Optical Activity	UNSPECIFIED
Defined Stereocenters	12 / 12
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of VOCLOSPORIN

Structure Search

SMILES

[H][C@@]1([C@H](O)[C@H](C)C\C=C\C=C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)[C@H](CC)NC1=O)C(C)C

InChI

InChIKey=BICRTLVBTLFLRD-PTWUADNWSA-N

InChI=1S/C63H111N11O12/c1-25-27-28-29-41(15)53(76)52-57(80)66-44(26-2)59(82)68(18)34-49(75)69(19)45(30-35(3)4)56(79)67-50(39(11)12)62(85)70(20)46(31-36(5)6)55(78)64-42(16)54(77)65-43(17)58(81)71(21)47(32-37(7)8)60(83)72(22)48(33-38(9)10)61(84)73(23)51(40(13)14)63(86)74(52)24/h25,27-28,35-48,50-53,76H,1,26,29-34H2,2-24H3,(H,64,78)(H,65,77)(H,66,80)(H,67,79)/b28-27+/t41-,42+,43-,44+,45+,46+,47+,48+,50+,51+,52+,53-/m1/s1

HIDE SMILES / InChI

Approval Year

Name

Type

Language

VOCLOSPORIN

Official Name

English

VOCLOSPORIN [MART.]

Common Name

English

VOCLOSPORIN [MI]

Common Name

English

ISA-247

Code

English

LUPKYNIS

Brand Name

English

CYCLO(L-ALANYL-D-ALANYL-N-METHYL-L-LEUCYL-N-METHYL-L-LEUCYL-N-METHYL-L-VALYL- ((2S,3R,4R,6E)-3-HYDROXY-4-METHYL-2-(METHYLAMINO)NONA-6,8-DIENOYL)-(2S)-2- AMINOBUTANOYL-N-METHYLGLYCYL-N-METHYL-L-LEUCYL-L-VALYL-N-METHYL-L-LEUCYL)

Common Name

English

Voclosporin [WHO-DD]

Common Name

English

voclosporin [INN]

Common Name

English

LX211

Code

English

CYCLOSPORIN A, 6-((2S,3R,4R,6E)-3-HYDROXY-4-METHYL-2-(METHYLAMINO)-6,8- NONADIENOIC ACID)-

Common Name

English

VOCLOSPORIN [USAN]

Common Name

English

LX-211

Code

English

VOCLOSPORIN [ORANGE BOOK]

Common Name

English

ISA247

Code

English

ISATX247

Code

English

CYCLO (((E,Z)-(2S,3R,4R)-3-HYDROXY-4-METHYL-2-(METHYLAMINO)NONA-6,8-DIENOYL)-L-2-AMINOBYTYRL-N-METHYL-GLYCYL-N-METHYL-L-LEUCYL-L-VALYL-N-METHYL-L-LEUCYL-L-ALANYL-D-ALANYL-N-METHYL-L-LEUCYL-N-METHYL-L-LEUCYL-N-METHYL-L-VALYL)

Common Name

English

ISATX-247

Code

English

Classification Tree Code System Code

EU-Orphan Drug

EU/3/12/1085

Created by admin on Fri Dec 15 15:43:14 UTC 2023 , Edited by admin on Fri Dec 15 15:43:14 UTC 2023

WHO-ATC

L04AD03

Created by admin on Fri Dec 15 15:43:14 UTC 2023 , Edited by admin on Fri Dec 15 15:43:14 UTC 2023

NCI_THESAURUS

C574

Created by admin on Fri Dec 15 15:43:14 UTC 2023 , Edited by admin on Fri Dec 15 15:43:14 UTC 2023

WHO-VATC

QL04AD03

Created by admin on Fri Dec 15 15:43:14 UTC 2023 , Edited by admin on Fri Dec 15 15:43:14 UTC 2023

FDA ORPHAN DRUG

227806

Created by admin on Fri Dec 15 15:43:14 UTC 2023 , Edited by admin on Fri Dec 15 15:43:14 UTC 2023

Code System Code Type Description

MERCK INDEX

m11494

Created by admin on Fri Dec 15 15:43:14 UTC 2023 , Edited by admin on Fri Dec 15 15:43:14 UTC 2023

PRIMARY

Merck Index

EVMPD

SUB31127

Created by admin on Fri Dec 15 15:43:14 UTC 2023 , Edited by admin on Fri Dec 15 15:43:14 UTC 2023

PRIMARY

CAS

515814-01-4

Created by admin on Fri Dec 15 15:43:14 UTC 2023 , Edited by admin on Fri Dec 15 15:43:14 UTC 2023

PRIMARY

USAN

SS-03

Created by admin on Fri Dec 15 15:43:14 UTC 2023 , Edited by admin on Fri Dec 15 15:43:14 UTC 2023

PRIMARY

DRUG CENTRAL

4366

Created by admin on Fri Dec 15 15:43:14 UTC 2023 , Edited by admin on Fri Dec 15 15:43:14 UTC 2023

PRIMARY

DRUG BANK

DB11693

Created by admin on Fri Dec 15 15:43:14 UTC 2023 , Edited by admin on Fri Dec 15 15:43:14 UTC 2023

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FDA UNII

2PN063X6B1

Created by admin on Fri Dec 15 15:43:14 UTC 2023 , Edited by admin on Fri Dec 15 15:43:14 UTC 2023

PRIMARY

SMS_ID

100000115486

Created by admin on Fri Dec 15 15:43:14 UTC 2023 , Edited by admin on Fri Dec 15 15:43:14 UTC 2023

PRIMARY

NCI_THESAURUS

C152902

Created by admin on Fri Dec 15 15:43:14 UTC 2023 , Edited by admin on Fri Dec 15 15:43:14 UTC 2023

PRIMARY

WIKIPEDIA

VOCLOSPORIN

Created by admin on Fri Dec 15 15:43:14 UTC 2023 , Edited by admin on Fri Dec 15 15:43:14 UTC 2023

PRIMARY

INN

8889

Created by admin on Fri Dec 15 15:43:14 UTC 2023 , Edited by admin on Fri Dec 15 15:43:14 UTC 2023

PRIMARY

ChEMBL

CHEMBL2218919

Created by admin on Fri Dec 15 15:43:14 UTC 2023 , Edited by admin on Fri Dec 15 15:43:14 UTC 2023

PRIMARY

RXCUI

2475166

Created by admin on Fri Dec 15 15:43:14 UTC 2023 , Edited by admin on Fri Dec 15 15:43:14 UTC 2023

PRIMARY

DAILYMED

2PN063X6B1

Created by admin on Fri Dec 15 15:43:14 UTC 2023 , Edited by admin on Fri Dec 15 15:43:14 UTC 2023

PRIMARY

PUBCHEM

6918486

Created by admin on Fri Dec 15 15:43:14 UTC 2023 , Edited by admin on Fri Dec 15 15:43:14 UTC 2023

PRIMARY

EPA CompTox

DTXSID401030488

Created by admin on Fri Dec 15 15:43:14 UTC 2023 , Edited by admin on Fri Dec 15 15:43:14 UTC 2023

PRIMARY

ACTIVE MOIETY


					2PN063X6B1