AVAPRITINIB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C26H27FN10
Molecular Weight	498.558
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of AVAPRITINIB

Structure Search

SMILES

CN1C=C(C=N1)C2=CN3N=CN=C(N4CCN(CC4)C5=NC=C(C=N5)[C@@](C)(N)C6=CC=C(F)C=C6)C3=C2

InChI

InChIKey=DWYRIWUZIJHQKQ-SANMLTNESA-N

InChI=1S/C26H27FN10/c1-26(28,20-3-5-22(27)6-4-20)21-13-29-25(30-14-21)36-9-7-35(8-10-36)24-23-11-18(16-37(23)33-17-31-24)19-12-32-34(2)15-19/h3-6,11-17H,7-10,28H2,1-2H3/t26-/m0/s1

HIDE SMILES / InChI

Approval Year

Name

Type

Language

AVAPRITINIB

Official Name

English

X-720776

Code

English

AYVAKIT

Brand Name

English

70C366

Code

English

AVAPRITINIB [MI]

Common Name

English

C-366

Code

English

(S)-1-(4-FLUOROPHENYL)-1-(2-(4-(6-(1-METHYL-1H-PYRAZOL-4-YL)PYRROLO(2,1-F)(1,2,4)TRIAZIN-4-YL)PIPERAZIN-YL)PYRIMIDIN-5-YL)ETHAN-1-AMINE

Systematic Name

English

AVAPRITINIB [ORANGE BOOK]

Common Name

English

5-PYRIMIDINEMETHANAMINE, .ALPHA.-(4-FLUOROPHENYL)-.ALPHA.-METHYL-2-(4-(6-(1-METHYL-1H-PYRAZOL-4-YL)PYRROLO(2,1-F)(1,2,4)TRIAZIN-4-YL)-1-PIPERAZINYL)-, (.ALPHA.S)-

Systematic Name

English

Avapritinib [WHO-DD]

Common Name

English

BLU-285

Code

English

X720776

Code

English

avapritinib [INN]

Common Name

English

AVAPRITINIB [USAN]

Common Name

English

(1S)-1-(4-Fluorophenyl)-1-(2-{4-[6-(1-methyl-1H-pyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]piperazin-1-yl}pyrimidin-5-yl)ethan-1-amine

Systematic Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

506515

Created by admin on Sat Dec 16 11:06:27 UTC 2023 , Edited by admin on Sat Dec 16 11:06:27 UTC 2023

EU-Orphan Drug

EU/3/18/2074

Created by admin on Sat Dec 16 11:06:27 UTC 2023 , Edited by admin on Sat Dec 16 11:06:27 UTC 2023

FDA ORPHAN DRUG

500415

Created by admin on Sat Dec 16 11:06:27 UTC 2023 , Edited by admin on Sat Dec 16 11:06:27 UTC 2023

Code System Code Type Description

CAS

1703793-34-3

Created by admin on Sat Dec 16 11:06:27 UTC 2023 , Edited by admin on Sat Dec 16 11:06:27 UTC 2023

PRIMARY

WIKIPEDIA

Avapritinib

Created by admin on Sat Dec 16 11:06:27 UTC 2023 , Edited by admin on Sat Dec 16 11:06:27 UTC 2023

PRIMARY

PUBCHEM

118023034

Created by admin on Sat Dec 16 11:06:27 UTC 2023 , Edited by admin on Sat Dec 16 11:06:27 UTC 2023

PRIMARY

EPA CompTox

DTXSID301027935

Created by admin on Sat Dec 16 11:06:27 UTC 2023 , Edited by admin on Sat Dec 16 11:06:27 UTC 2023

PRIMARY

DAILYMED

513P80B4YJ

Created by admin on Sat Dec 16 11:06:27 UTC 2023 , Edited by admin on Sat Dec 16 11:06:27 UTC 2023

PRIMARY

DRUG CENTRAL

5379

Created by admin on Sat Dec 16 11:06:27 UTC 2023 , Edited by admin on Sat Dec 16 11:06:27 UTC 2023

PRIMARY

DRUG BANK

DB15233

Created by admin on Sat Dec 16 11:06:27 UTC 2023 , Edited by admin on Sat Dec 16 11:06:27 UTC 2023

PRIMARY

RXCUI

2272107

Created by admin on Sat Dec 16 11:06:27 UTC 2023 , Edited by admin on Sat Dec 16 11:06:27 UTC 2023

PRIMARY

USAN

FG-25

Created by admin on Sat Dec 16 11:06:27 UTC 2023 , Edited by admin on Sat Dec 16 11:06:27 UTC 2023

PRIMARY

LACTMED

Avapritinib

Created by admin on Sat Dec 16 11:06:27 UTC 2023 , Edited by admin on Sat Dec 16 11:06:27 UTC 2023

PRIMARY

FDA UNII

513P80B4YJ

Created by admin on Sat Dec 16 11:06:27 UTC 2023 , Edited by admin on Sat Dec 16 11:06:27 UTC 2023

PRIMARY

NCI_THESAURUS

C123827

Created by admin on Sat Dec 16 11:06:27 UTC 2023 , Edited by admin on Sat Dec 16 11:06:27 UTC 2023

PRIMARY

INN

10613

Created by admin on Sat Dec 16 11:06:27 UTC 2023 , Edited by admin on Sat Dec 16 11:06:27 UTC 2023

PRIMARY

SMS_ID

100000177408

Created by admin on Sat Dec 16 11:06:27 UTC 2023 , Edited by admin on Sat Dec 16 11:06:27 UTC 2023

PRIMARY

MERCK INDEX

m12190

Created by admin on Sat Dec 16 11:06:27 UTC 2023 , Edited by admin on Sat Dec 16 11:06:27 UTC 2023

PRIMARY

ACTIVE MOIETY


					513P80B4YJ