FENCLORAC

Details

Stereochemistry	RACEMIC
Molecular Formula	C14H16Cl2O2
Molecular Weight	287.182
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)C(Cl)C1=CC=C(C2CCCCC2)C(Cl)=C1

InChI

InChIKey=GXEUNRBWEAIPCN-UHFFFAOYSA-N

InChI=1S/C14H16Cl2O2/c15-12-8-10(13(16)14(17)18)6-7-11(12)9-4-2-1-3-5-9/h6-9,13H,1-5H2,(H,17,18)

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Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1008019 | https://www.ncbi.nlm.nih.gov/pubmed/18151 | https://www.ncbi.nlm.nih.gov/pubmed/409117

Fenclorac is a potent nonsteroidal anti-inflammatory agent with significant analgesic and antipyretic activity. It inhibits prostaglandin synthesis both in vitro and in vivo.

Approval Year

PubMed

Title	Date	PubMed
The inhibition of prostaglandin synthetase in vivo by nonsteroidal anti-inflammatory agents.	1977-07	409117
Studies on the in vitro inhibition of prostaglandin synthetase by fenclorac (alpha, m-dichloro-p-cyclohexylphenylacetic acid) and indomethacin.	1977-06-01	18151
The antiphlogistic, antinociceptive and antipyretic properties of fenclorac.	1976-11	1008019
Inhibition of the diarrheal and cardiac actions of arachidonic acid by fenclorac, a new anti-inflammatory agent.	1976-10-15	994722

Name

Type

Language

FENCLORAC

Official Name

English

WHR-539

Preferred Name

English

FENCLORAC [USAN]

Common Name

English

fenclorac [INN]

Common Name

English

Chloro(3-chloro-4-cyclohexylphenyl)acetic acid

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1323