MK-1903

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C8H8N2O2
Molecular Weight	164.1613
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@]12C[C@@]1([H])C3=C(C2)C(=NN3)C(O)=O

InChI

InChIKey=CUTZNERBKDMLAP-QWWZWVQMSA-N

InChI=1S/C8H8N2O2/c11-8(12)7-5-2-3-1-4(3)6(5)9-10-7/h3-4H,1-2H2,(H,9,10)(H,11,12)/t3-,4-/m1/s1

HIDE SMILES / InChI

Approval Year

Name

Type

Language

MK-1903

Common Name

English

(4AR,5AR)-4,4A,5,5A-TETRAHYDRO-1H-CYCLOPROPA(4,5)CYCLOPENTA(1,2-C)PYRAZOLE-3-CARBOXYLIC ACID

Systematic Name

English

1H-CYCLOPROPA(4,5)CYCLOPENTA(1,2-C)PYRAZOLE-3-CARBOXYLIC ACID, 4,4A,5,5A-TETRAHYDRO-, (4AR,5AR)-

Systematic Name

English

Code System Code Type Description

CAS

1268882-43-4

Created by admin on Sat Dec 16 11:46:03 UTC 2023 , Edited by admin on Sat Dec 16 11:46:03 UTC 2023

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PUBCHEM

49763030

Created by admin on Sat Dec 16 11:46:03 UTC 2023 , Edited by admin on Sat Dec 16 11:46:03 UTC 2023

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MANUFACTURER PRODUCT INFORMATION

MK-1903

Created by admin on Sat Dec 16 11:46:03 UTC 2023 , Edited by admin on Sat Dec 16 11:46:03 UTC 2023

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Biological Activity: Potent and selective hydroxycarboxylic acid receptor 2 (HCA2, GPR109A) full agonist; exhibits greater potency than niacin in a whole cell HTRF-cAMP assay (EC50 values are 12.9 and 51 nM respectively). Exhibits no binding at the GRP109B receptor.

FDA UNII

62N05GRI0P

Created by admin on Sat Dec 16 11:46:03 UTC 2023 , Edited by admin on Sat Dec 16 11:46:03 UTC 2023

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ACTIVE MOIETY


					62N05GRI0P

MK-1903