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Details

Stereochemistry ABSOLUTE
Molecular Formula C23H23N3O5.ClH
Molecular Weight 457.907
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TOPOTECAN HYDROCHLORIDE

SMILES

Cl.CC[C@@]1(O)C(=O)OCC2=C1C=C3N(CC4=C3N=C5C=CC(O)=C(CN(C)C)C5=C4)C2=O

InChI

InChIKey=DGHHQBMTXTWTJV-BQAIUKQQSA-N
InChI=1S/C23H23N3O5.ClH/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20;/h5-8,27,30H,4,9-11H2,1-3H3;1H/t23-;/m0./s1

HIDE SMILES / InChI

Approval Year

Unknown
86413
Name Type Language
TOPOTECAN HYDROCHLORIDE
MART.   MI   ORANGE BOOK   USAN   USP-RS   VANDF   WHO-DD  
USAN  
Official Name English
TOPOTECAN ACTAVIS
Brand Name English
(S)-10-((DIMETHYLAMINO)METHYL)-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO(3',4':6,7)INDOLIZINO(1,2-B)QUINOLINE-3,14(4H,12H)-DIONE MONOHYDROCHLORIDE
Systematic Name English
1H-PYRANO(3',4':6,7)INDOLIZINO(1,2-B)QUINOLINE-3,14(4H,12H)-DIONE, 10-((DIMETHYLAMINO)METHYL)-4-ETHYL-4,9-DIHYDROXY-, MONOHYDROCHLORIDE, (S)-
Common Name English
EVOTOPIN
Brand Name English
TOPOTECAN HYDROCHLORIDE [USAN]
Common Name English
SK&F S-104864-A
Code English
TOPOTECAN HYDROCHLORIDE [MI]
Common Name English
TOPOTECAN HYDROCHLORIDE [VANDF]
Common Name English
HYCAMTIN
Brand Name English
NOGITECAN HYDROCHLORIDE
JAN  
Common Name English
TOPOTECAN HYDROCHLORIDE [USP-RS]
Common Name English
TOPOTECAN (AS HYDROCHLORIDE)
Common Name English
TOPOTECAN HCL
Common Name English
TOPOTECAN HOSPIRA
Brand Name English
NOGITECAN HYDROCHLORIDE [JAN]
Common Name English
Topotecan hydrochloride [WHO-DD]
Common Name English
POTACTASOL
Brand Name English
NSC-759263
Code English
TOPOTECAN HYDROCHLORIDE [ORANGE BOOK]
Common Name English
SK&F-S-104864-A
Code English
TOPOTECAN TEVA
Brand Name English
TOPOTECAN HYDROCHLORIDE [MART.]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 268508
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
EMA ASSESSMENT REPORTS POTACTASOL (AUTHORIZED: UTERINE CERVICAL NEOPLASMS)
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
EMA ASSESSMENT REPORTS TOPOTECAN TEVA (AUTHORIZED: UTERINE CERVICAL NEOPLASMS)
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
EMA ASSESSMENT REPORTS HYCAMTIN (AUTHORIZED: UTERINE CERVICAL NEOPLASMS)
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
EMA ASSESSMENT REPORTS TOPOTECAN EAGLE (WITHDRAWN SMALL CELL LUNG CARCINOMA)
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
EMA ASSESSMENT REPORTS TOPOTECAN TEVA (AUTHORIZED: OVARIAN NEOPLASMS)
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
EMA ASSESSMENT REPORTS EVOTOPIN (WITHDRAWN: OVARIAN NEOPLASMS)
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
NCI_THESAURUS C2843
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
EMA ASSESSMENT REPORTS TOPOTECAN ACTAVIS (AUTHORIZED: UTERINE CERVICAL NEOPLASMS)
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
EU-Orphan Drug EU/3/08/562
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
EMA ASSESSMENT REPORTS HYCAMTIN (AUTHORIZED: OVARIAN NEOPLASMS)
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
EMA ASSESSMENT REPORTS TOPOTECAN HOSPIRA (AUTHORIZED: UTERINE CERVICAL NEOPLASMS)
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
Code System Code Type Description
ChEMBL
CHEMBL84
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
PRIMARY
DRUG BANK
DB01030
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
PRIMARY
RXCUI
266573
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
PRIMARY RxNorm
FDA UNII
956S425ZCY
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
PRIMARY
DAILYMED
956S425ZCY
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
PRIMARY
PUBCHEM
60699
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
PRIMARY
USAN
BB-40
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
PRIMARY
RS_ITEM_NUM
1672257
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
PRIMARY
CAS
119413-54-6
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
PRIMARY
EVMPD
SUB04921MIG
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
PRIMARY
NCI_THESAURUS
C2828
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
PRIMARY
MERCK INDEX
m10977
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
PRIMARY Merck Index
SMS_ID
100000091113
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
PRIMARY
EPA CompTox
DTXSID1045952
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
PRIMARY
NSC
759263
Created by admin on Fri Dec 15 16:35:26 UTC 2023 , Edited by admin on Fri Dec 15 16:35:26 UTC 2023
PRIMARY
PARENT (SALT/SOLVATE)
Structure of TOPOTECAN
NIH
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