Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C26H23N2O6S.Na |
| Molecular Weight | 514.525 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].COC1=CC=C(N=C1)C2=CC=C(OCC3=C(C)OC(=C3)C(=O)[N-]S(=O)(=O)C4=CC=CC=C4C)C=C2
InChI
InChIKey=TVDHMDXPKGMXRT-UHFFFAOYSA-M
InChI=1S/C26H24N2O6S.Na/c1-17-6-4-5-7-25(17)35(30,31)28-26(29)24-14-20(18(2)34-24)16-33-21-10-8-19(9-11-21)23-13-12-22(32-3)15-27-23;/h4-15H,16H2,1-3H3,(H,28,29);/q;+1/p-1
Approval Year
| Name | Type | Language | ||
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Code | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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300000042403
Created by
admin on Sat Dec 16 11:31:13 UTC 2023 , Edited by admin on Sat Dec 16 11:31:13 UTC 2023
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PRIMARY | |||
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1186532-61-5
Created by
admin on Sat Dec 16 11:31:13 UTC 2023 , Edited by admin on Sat Dec 16 11:31:13 UTC 2023
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PRIMARY | |||
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BGC-20-1531
Created by
admin on Sat Dec 16 11:31:13 UTC 2023 , Edited by admin on Sat Dec 16 11:31:13 UTC 2023
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PRIMARY | Chemical Name: 4-((4-(5-Methoxy-2-pyridinyl)phenoxy)methyl)-5-methyl-N-((2-methylphenyl)sulfonyl)-2-furancarboxamide hydrochloride Biological Activity: High affinity and selective EP4 antagonist (Ki = 3 nM). Exhibits >2500-fold selectivity for EP4 over EP2 and EP3. Also selective over a range of other prostanoid receptors, ion channels, transporters and enzymes. Inhibits PGE2-induced vasodilation of middle cerebral and meningeal arteries in vitro, and carotid blood flow in vivo. Orally bioavailable. | ||
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25209437
Created by
admin on Sat Dec 16 11:31:13 UTC 2023 , Edited by admin on Sat Dec 16 11:31:13 UTC 2023
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PRIMARY | |||
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9QV7JG4XYZ
Created by
admin on Sat Dec 16 11:31:13 UTC 2023 , Edited by admin on Sat Dec 16 11:31:13 UTC 2023
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PRIMARY |
ACTIVE MOIETY
