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Details

Stereochemistry ABSOLUTE
Molecular Formula C20H18ClF2N5O3
Molecular Weight 449.838
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ASCIMINIB

SMILES

O[C@@H]1CCN(C1)C2=C(C=C(C=N2)C(=O)NC3=CC=C(OC(F)(F)Cl)C=C3)C4=CC=NN4

InChI

InChIKey=VOVZXURTCKPRDQ-CQSZACIVSA-N
InChI=1S/C20H18ClF2N5O3/c21-20(22,23)31-15-3-1-13(2-4-15)26-19(30)12-9-16(17-5-7-25-27-17)18(24-10-12)28-8-6-14(29)11-28/h1-5,7,9-10,14,29H,6,8,11H2,(H,25,27)(H,26,30)/t14-/m1/s1

HIDE SMILES / InChI

Approval Year

Unknown
123738
Name Type Language
ASCIMINIB
INN   WHO-DD  
USAN   INN  
Official Name English
Asciminib [WHO-DD]
Common Name English
ABL-001
Code English
ABL001
Code English
N-(4-(CHLORODIFLUOROMETHOXY)PHENYL)-6-((3R)-3- HYDROXYPYRROLIDIN-1-YL)-5-(1H-PYRAZOL-3-YL)PYRIDINE- 3-CARBOXAMIDE
Systematic Name English
asciminib [INN]
Common Name English
3-PYRIDINECARBOXAMIDE, N-(4-(CHLORODIFLUOROMETHOXY)PHENYL)-6-((3R)-3-HYDROXY-1-PYRROLIDINYL)-5-(1H-PYRAZOL-3-YL)-
Systematic Name English
NVP-ABL001
Code English
ABL001-NX
Code English
ASCIMINIB [USAN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C1967
Created by admin on Sat Dec 16 18:03:02 UTC 2023 , Edited by admin on Sat Dec 16 18:03:02 UTC 2023
FDA ORPHAN DRUG 556416
Created by admin on Sat Dec 16 18:03:02 UTC 2023 , Edited by admin on Sat Dec 16 18:03:02 UTC 2023
NCI_THESAURUS C129825
Created by admin on Sat Dec 16 18:03:02 UTC 2023 , Edited by admin on Sat Dec 16 18:03:02 UTC 2023
Code System Code Type Description
FDA UNII
L1F3R18W77
Created by admin on Sat Dec 16 18:03:02 UTC 2023 , Edited by admin on Sat Dec 16 18:03:02 UTC 2023
PRIMARY
ChEMBL
CHEMBL3545115
Created by admin on Sat Dec 16 18:03:02 UTC 2023 , Edited by admin on Sat Dec 16 18:03:02 UTC 2023
PRIMARY
SMS_ID
100000174619
Created by admin on Sat Dec 16 18:03:02 UTC 2023 , Edited by admin on Sat Dec 16 18:03:02 UTC 2023
PRIMARY
RXCUI
2584304
Created by admin on Sat Dec 16 18:03:02 UTC 2023 , Edited by admin on Sat Dec 16 18:03:02 UTC 2023
PRIMARY
USAN
FG-57
Created by admin on Sat Dec 16 18:03:02 UTC 2023 , Edited by admin on Sat Dec 16 18:03:02 UTC 2023
PRIMARY
NCI_THESAURUS
C114494
Created by admin on Sat Dec 16 18:03:02 UTC 2023 , Edited by admin on Sat Dec 16 18:03:02 UTC 2023
PRIMARY
CAS
1492952-76-7
Created by admin on Sat Dec 16 18:03:02 UTC 2023 , Edited by admin on Sat Dec 16 18:03:02 UTC 2023
PRIMARY
DRUG BANK
DB12597
Created by admin on Sat Dec 16 18:03:02 UTC 2023 , Edited by admin on Sat Dec 16 18:03:02 UTC 2023
PRIMARY
PUBCHEM
72165228
Created by admin on Sat Dec 16 18:03:02 UTC 2023 , Edited by admin on Sat Dec 16 18:03:02 UTC 2023
PRIMARY
INN
10267
Created by admin on Sat Dec 16 18:03:02 UTC 2023 , Edited by admin on Sat Dec 16 18:03:02 UTC 2023
PRIMARY
DAILYMED
L1F3R18W77
Created by admin on Sat Dec 16 18:03:02 UTC 2023 , Edited by admin on Sat Dec 16 18:03:02 UTC 2023
PRIMARY
ACTIVE MOIETY
Structure of ASCIMINIB
SALT/SOLVATE (PARENT)
Structure of ASCIMINIB HYDROCHLORIDE
NIH
NCATS
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