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Details

Stereochemistry ABSOLUTE
Molecular Formula C13H24N4O3S.C4H4O4
Molecular Weight 432.492
Optical Activity ( - )
Defined Stereocenters 1 / 1
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of TIMOLOL MALEATE

SMILES

OC(=O)\C=C/C(O)=O.CC(C)(C)NC[C@H](O)COC1=NSN=C1N2CCOCC2

InChI

InChIKey=WLRMANUAADYWEA-NWASOUNVSA-N
InChI=1S/C13H24N4O3S.C4H4O4/c1-13(2,3)14-8-10(18)9-20-12-11(15-21-16-12)17-4-6-19-7-5-17;5-3(6)1-2-4(7)8/h10,14,18H,4-9H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t10-;/m0./s1

HIDE SMILES / InChI

Approval Year

Unknown
86413
Name Type Language
TIMOLOL MALEATE
EP   MART.   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD   WHO-IP  
USAN  
Official Name English
TIMOLOL MALEATE COMPONENT OF COMBIGAN
Common Name English
TIMOPTIC
Brand Name English
DUOTRAV COMPONENT TIMOLOL MALEATE
Brand Name English
(-)-1-(TERT-BUTYLAMINO)-3-((4-MORPHOLINO-1,2,5-THIADIAZOL-3-YL)OXY)-2-PROPANOL MALEATE (1:1) (SALT)
Common Name English
2-PROPANOL, 1-((1,1-DIMETHYLETHYL)AMINO)-3-((4-(4-MORPHOLINYL)-1,2,5-THIADIAZOL-3-YL)OXY)-, (S)-, (Z)-2-BUTENEDIOATE (1:1) (SALT)
Common Name English
TIMOLOL MALEATE COMPONENT OF DUOTRAV
Brand Name English
COSOPT COMPONENT TIMOLOL MALEATE
Common Name English
TIMOLOL MALEATE, S-ENANTIOMER
WHO-DD  
Common Name English
TIMOLOL HYDROGEN MALEATE SALT
MI  
Common Name English
TIMOLOL MALEATE [USP-RS]
Common Name English
WP-934
Code English
TIMOLOL (AS MALEATE)
Common Name English
TIMOLOL MALEATE COMPONENT OF COSOPT
Common Name English
TIMOLOL MALEATE [ORANGE BOOK]
Common Name English
GANFORT COMPONENT TIMOLOL MALEATE
Brand Name English
NSC-757351
Code English
XALACOM COMPONENT TIMOLOL MALEATE
Brand Name English
COMBIGAN COMPONENT TIMOLOL MALEATE
Common Name English
ISTALOL
Brand Name English
AQUANIL
Common Name English
TIMOLOL MALEATE [USP MONOGRAPH]
Common Name English
TIMOLOL MALEATE COMPONENT OF GANFORT
Brand Name English
Timolol maleate [WHO-DD]
Common Name English
TIMOLOL MALEATE [MART.]
Common Name English
TIMOLOL MALEATE [EP MONOGRAPH]
Common Name English
TIMOLOL MALEATE [WHO-IP]
Common Name English
OPHTAMOLOL
Common Name English
BLOCADREN
Brand Name English
TIMOLOL MALEATE [USAN]
Common Name English
TIMOLOLI MALEAS [WHO-IP LATIN]
Common Name English
TIMOLOL MALEATE [JAN]
Common Name English
Timolol maleate, s-enantiomer [WHO-DD]
Common Name English
TIMOLOL MALEATE [USP IMPURITY]
Common Name English
TIMOLOL HYDROGEN MALEATE SALT [MI]
Common Name English
TIMOLOL MALEATE [VANDF]
Common Name English
Classification Tree Code System Code
EMA ASSESSMENT REPORTS DUOTRAV (AUTHORIZED: OCULAR HYPERTENSION)
Created by admin on Fri Dec 15 16:03:39 UTC 2023 , Edited by admin on Fri Dec 15 16:03:39 UTC 2023
NCI_THESAURUS C29576
Created by admin on Fri Dec 15 16:03:39 UTC 2023 , Edited by admin on Fri Dec 15 16:03:39 UTC 2023
EMA ASSESSMENT REPORTS GANFORT (AUTHORIZED: OCULAR HYPERTENSION)
Created by admin on Fri Dec 15 16:03:39 UTC 2023 , Edited by admin on Fri Dec 15 16:03:39 UTC 2023
EMA ASSESSMENT REPORTS AZARGA (AUTHORIZED: GLAUCOMA, OPEN-ANGLE)
Created by admin on Fri Dec 15 16:03:39 UTC 2023 , Edited by admin on Fri Dec 15 16:03:39 UTC 2023
EMA ASSESSMENT REPORTS GANFORT (AUTHORIZED: GLAUCOMA, OPEN-ANGLE)
Created by admin on Fri Dec 15 16:03:39 UTC 2023 , Edited by admin on Fri Dec 15 16:03:39 UTC 2023
EMA ASSESSMENT REPORTS DUOTRAV (AUTHORIZED: GLAUCOMA, OPEN-ANGLE)
Created by admin on Fri Dec 15 16:03:39 UTC 2023 , Edited by admin on Fri Dec 15 16:03:39 UTC 2023
Code System Code Type Description
EVMPD
SUB04877MIG
Created by admin on Fri Dec 15 16:03:39 UTC 2023 , Edited by admin on Fri Dec 15 16:03:39 UTC 2023
PRIMARY
FDA UNII
P8Y54F701R
Created by admin on Fri Dec 15 16:03:39 UTC 2023 , Edited by admin on Fri Dec 15 16:03:39 UTC 2023
PRIMARY
NCI_THESAURUS
C29501
Created by admin on Fri Dec 15 16:03:39 UTC 2023 , Edited by admin on Fri Dec 15 16:03:39 UTC 2023
PRIMARY
EVMPD
SUB04875MIG
Created by admin on Fri Dec 15 16:03:39 UTC 2023 , Edited by admin on Fri Dec 15 16:03:39 UTC 2023
PRIMARY
EPA CompTox
DTXSID3047504
Created by admin on Fri Dec 15 16:03:39 UTC 2023 , Edited by admin on Fri Dec 15 16:03:39 UTC 2023
PRIMARY
ChEMBL
CHEMBL499
Created by admin on Fri Dec 15 16:03:39 UTC 2023 , Edited by admin on Fri Dec 15 16:03:39 UTC 2023
PRIMARY
DAILYMED
P8Y54F701R
Created by admin on Fri Dec 15 16:03:39 UTC 2023 , Edited by admin on Fri Dec 15 16:03:39 UTC 2023
PRIMARY
SMS_ID
100000090033
Created by admin on Fri Dec 15 16:03:39 UTC 2023 , Edited by admin on Fri Dec 15 16:03:39 UTC 2023
PRIMARY
MERCK INDEX
m10871
Created by admin on Fri Dec 15 16:03:39 UTC 2023 , Edited by admin on Fri Dec 15 16:03:39 UTC 2023
PRIMARY Merck Index
DRUG BANK
DBSALT000989
Created by admin on Fri Dec 15 16:03:39 UTC 2023 , Edited by admin on Fri Dec 15 16:03:39 UTC 2023
PRIMARY
RXCUI
42933
Created by admin on Fri Dec 15 16:03:39 UTC 2023 , Edited by admin on Fri Dec 15 16:03:39 UTC 2023
PRIMARY RxNorm
NSC
757351
Created by admin on Fri Dec 15 16:03:39 UTC 2023 , Edited by admin on Fri Dec 15 16:03:39 UTC 2023
PRIMARY
ECHA (EC/EINECS)
248-111-5
Created by admin on Fri Dec 15 16:03:39 UTC 2023 , Edited by admin on Fri Dec 15 16:03:39 UTC 2023
PRIMARY
CAS
26921-17-5
Created by admin on Fri Dec 15 16:03:39 UTC 2023 , Edited by admin on Fri Dec 15 16:03:39 UTC 2023
PRIMARY
PUBCHEM
5281056
Created by admin on Fri Dec 15 16:03:39 UTC 2023 , Edited by admin on Fri Dec 15 16:03:39 UTC 2023
PRIMARY
CHEBI
9600
Created by admin on Fri Dec 15 16:03:39 UTC 2023 , Edited by admin on Fri Dec 15 16:03:39 UTC 2023
PRIMARY
RS_ITEM_NUM
1667406
Created by admin on Fri Dec 15 16:03:39 UTC 2023 , Edited by admin on Fri Dec 15 16:03:39 UTC 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
TIMOLOL MALEATE
Created by admin on Fri Dec 15 16:03:39 UTC 2023 , Edited by admin on Fri Dec 15 16:03:39 UTC 2023
PRIMARY Description: A white or almost white powder; odourless or almost odourless. Solubility: Soluble in water, methanol R, and ethanol (~750 g/l) TS; practically insoluble in ether R. Category: Antiglaucoma drug. Storage: Timolol maleate should be kept in a well-closed container, protected from light. Requirement: Timolol maleate contains not less than 98.0% and not more than the equivalent of 101.0% of C13H24N4O3S,C4H4O4, calculated with reference to the dried substance.
PARENT (SALT/SOLVATE)
Structure of MALEIC ACID
SUBSTANCE RECORD
Structure of TIMOLOL MALEATE
NIH
NCATS
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