ABIVERTINIB MALEATE ANHYDROUS

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	C26H26FN7O2.C4H4O4
Molecular Weight	603.6009
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of ABIVERTINIB MALEATE ANHYDROUS

Structure Search

SMILES

OC(=O)\C=C/C(O)=O.CN1CCN(CC1)C2=CC=C(NC3=NC4=C(C=CN4)C(OC5=CC(NC(=O)C=C)=CC=C5)=N3)C=C2F

InChI

InChIKey=VRHPZWLHPIENFW-BTJKTKAUSA-N

InChI=1S/C26H26FN7O2.C4H4O4/c1-3-23(35)29-17-5-4-6-19(15-17)36-25-20-9-10-28-24(20)31-26(32-25)30-18-7-8-22(21(27)16-18)34-13-11-33(2)12-14-34;5-3(6)1-2-4(7)8/h3-10,15-16H,1,11-14H2,2H3,(H,29,35)(H2,28,30,31,32);1-2H,(H,5,6)(H,7,8)/b;2-1-

HIDE SMILES / InChI

Molecular Formula	C26H26FN7O2
Molecular Weight	487.5287
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C4H4O4
Molecular Weight	116.0722
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Epidermal growth factor receptor 49 Target ID: CHEMBL2363049 Sources: https://www.ncbi.nlm.nih.gov/pubmed/28414972	Inhibitor 8504

Substance Class	Chemical Created by `admin` on `Tue Apr 01 22:21:18 GMT 2025` Edited by `admin` on `Tue Apr 01 22:21:18 GMT 2025`
Record UNII	0447KM2XTD
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

AVITINIB MALEATE

Preferred Name

English

ABIVERTINIB MALEATE ANHYDROUS

Common Name

English

2-PROPENAMIDE, N-(3-((2-((3-FLUORO-4-(4-METHYL-1-PIPERAZINYL)PHENYL)AMINO)-7H-PYRROLO(2,3-D)PYRIMIDIN-4-YL)OXY)PHENYL)-, (2Z)-2-BUTENEDIOATE (1:1)

Systematic Name

English

Avitinib maleate [WHO-DD]

Common Name

English

Code System Code Type Description

PUBCHEM

121596128