Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C16H25NO2 |
| Molecular Weight | 263.3752 |
| Optical Activity | ( + ) |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN(C)C[C@H](C1=CC=C(O)C=C1)C2(O)CCCCC2
InChI
InChIKey=KYYIDSXMWOZKMP-OAHLLOKOSA-N
InChI=1S/C16H25NO2/c1-17(2)12-15(13-6-8-14(18)9-7-13)16(19)10-4-3-5-11-16/h6-9,15,18-19H,3-5,10-12H2,1-2H3/t15-/m1/s1
| Molecular Formula | C16H25NO2 |
| Molecular Weight | 263.3752 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Prescription drugs associated with reports of violence towards others. | 2010-12-15 |
|
| Can depression be a menopause-associated risk? | 2010-12-01 |
|
| Desvenlafaxine for major depressive disorder: incremental clinical benefits from a second-generation serotonin-norepinephrine reuptake inhibitor. | 2010-12 |
|
| Assessment of infant dose through milk in a lactating woman taking amisulpride and desvenlafaxine for treatment-resistant depression. | 2010-12 |
|
| Managing menopausal symptoms and depression in tamoxifen users: implications of drug and medicinal interactions. | 2010-12 |
|
| Gene expression profile analysis of genes in rat hippocampus from antidepressant treated rats using DNA microarray. | 2010-11-30 |
|
| HAM-D17 and HAM-D6 sensitivity to change in relation to desvenlafaxine dose and baseline depression severity in major depressive disorder. | 2010-11 |
|
| Nonhormonal management of hot flashes for women on risk reduction therapy. | 2010-10 |
|
| Getting the balance right: Established and emerging therapies for major depressive disorders. | 2010-09-07 |
|
| Milnacipran: a unique antidepressant? | 2010-09-07 |
|
| Actual status of veralipride use. | 2010-09-07 |
|
| [Brazilian guidelines for the treatment of narcolepsy]. | 2010-09 |
|
| Optimal management of perimenopausal depression. | 2010-08-09 |
|
| Management of menopause-associated vasomotor symptoms: Current treatment options, challenges and future directions. | 2010-08-09 |
|
| Pharmacological and clinical profile of newer antidepressants: implications for the treatment of elderly patients. | 2010-08-01 |
|
| Short-term efficacy and safety of desvenlafaxine in a randomized, placebo-controlled study of perimenopausal and postmenopausal women with major depressive disorder. | 2010-08 |
|
| Retrospective analysis of suicidality in patients treated with the antidepressant desvenlafaxine. | 2010-08 |
|
| Desvenlafaxine and escitalopram for the treatment of postmenopausal women with major depressive disorder. | 2010-07 |
|
| Pharmaceutical treatment of acute bipolar depression. | 2010-06-23 |
|
| Desvenlafaxine in major depressive disorder: an evidence-based review of its place in therapy. | 2010-06-15 |
|
| Analysis by age and sex of efficacy data from placebo-controlled trials of desvenlafaxine in outpatients with major depressive disorder. | 2010-06 |
|
| Update on antithrombotic therapy for stroke prevention in atrial fibrillation. | 2010-06 |
|
| Desvenlafaxine: a therapeutic option for treatment of menopausal hot flashes. | 2010-05 |
|
| The emerging modern face of mood disorders: a didactic editorial with a detailed presentation of data and definitions. | 2010-04-12 |
|
| Desvenlafaxine as a possible cause of acquired hemophilia. | 2010-04-04 |
|
| Chronic thromboembolic pulmonary hypertension. | 2010-04 |
|
| Analysis of the effect of desvenlafaxine on anxiety symptoms associated with major depressive disorder: pooled data from 9 short-term, double-blind, placebo-controlled trials. | 2010-03 |
|
| Desvenlafaxine for the prevention of relapse in major depressive disorder: results of a randomized trial. | 2010-02 |
|
| What can be done about hot flushes after treatment for breast cancer? | 2010-02 |
|
| Desvenlafaxine. | 2010-01-06 |
|
| Correction of venlafaxine- and duloxetine-induced transaminase elevations with desvenlafaxine in a patient with Gilbert's syndrome. | 2010-01 |
|
| Desvenlafaxine succinate: a newer antidepressant for the treatment of depression and somatic symptoms. | 2010-01 |
|
| Mania possibly induced by desvenlafaxine. | 2010-01 |
|
| Clinical utility of desvenlafaxine 50 mg/d for treating MDD: a review of two randomized placebo-controlled trials for the practicing physician. | 2010-01 |
|
| A comparative study on the effects of Hypericum Perforatum and passion flower on the menopausal symptoms of women referring to Isfahan city health care centers. | 2010 |
|
| Efficacy, safety, and tolerability of Desvenlafaxine 50 mg/d for the treatment of major depressive disorder:a systematic review of clinical trials. | 2010 |
|
| Desvenlafaxine and weight change in major depressive disorder. | 2010 |
|
| Treatment of psychotic symptoms in bipolar disorder with aripiprazole monotherapy: a meta-analysis. | 2009-12-31 |
|
| Interactions between tamoxifen and antidepressants via cytochrome P450 2D6. | 2009-12 |
|
| Use of antidepressants for management of hot flashes. | 2009-11 |
|
| Discontinuation symptoms and taper/poststudy-emergent adverse events with desvenlafaxine treatment for major depressive disorder. | 2009-11 |
|
| Undertreatment of menopausal symptoms and novel options for comprehensive management. | 2009-11 |
|
| Assessing the efficacy of desvenlafaxine for improving functioning and well-being outcome measures in patients with major depressive disorder: a pooled analysis of 9 double-blind, placebo-controlled, 8-week clinical trials. | 2009-10 |
|
| [Non-hormonal treatment for vasomotor symptoms during menopause: role of desvenlafaxine]. | 2009-10 |
|
| Desvenlafaxine: application withdrawal. Desvenlafaxine: withdrawal of marketing application for depression also. | 2009-10 |
|
| Duloxetine for the management of fibromyalgia syndrome. | 2009-07-21 |
|
| Desvenlafaxine 50 and 100 mg/d in the treatment of major depressive disorder: an 8-week, phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group trial and a post hoc pooled analysis of three studies. | 2009-06 |
|
| Desvenlafaxine: a new serotonin-norepinephrine reuptake inhibitor for the treatment of adults with major depressive disorder. | 2009-06 |
|
| Analysis of depressive symptoms in patients with major depressive disorder treated with desvenlafaxine or placebo. | 2009 |
|
| Antidepressant prescribing by specialty and treatment of premenstrual dysphoric disorder. | 2008-12 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 20:54:09 GMT 2025
by
admin
on
Mon Mar 31 20:54:09 GMT 2025
|
| Record UNII |
189BFR45S0
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
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9816723
Created by
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142761-12-4
Created by
admin on Mon Mar 31 20:54:09 GMT 2025 , Edited by admin on Mon Mar 31 20:54:09 GMT 2025
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PRIMARY | |||
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189BFR45S0
Created by
admin on Mon Mar 31 20:54:09 GMT 2025 , Edited by admin on Mon Mar 31 20:54:09 GMT 2025
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PRIMARY | |||
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273749-38-5
Created by
admin on Mon Mar 31 20:54:09 GMT 2025 , Edited by admin on Mon Mar 31 20:54:09 GMT 2025
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SUPERSEDED |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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RACEMATE -> ENANTIOMER |
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