N-DESMETHYLVENLAFAXINE

Details

Stereochemistry	RACEMIC
Molecular Formula	C16H25NO2
Molecular Weight	263.3752
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CNCC(C1=CC=C(OC)C=C1)C2(O)CCCCC2

InChI

InChIKey=MKAFOJAJJMUXLW-UHFFFAOYSA-N

InChI=1S/C16H25NO2/c1-17-12-15(16(18)10-4-3-5-11-16)13-6-8-14(19-2)9-7-13/h6-9,15,17-18H,3-5,10-12H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C16H25NO2
Molecular Weight	263.3752
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Norepinephrine transporter 197 Target ID: CHEMBL222 Sources: https://www.ncbi.nlm.nih.gov/pubmed/1976813	Inhibitor 8504		4700.0 nM [IC50]
Serotonin transporter 183 Target ID: CHEMBL228 Sources: https://www.ncbi.nlm.nih.gov/pubmed/1976813	Inhibitor 8504		1600.0 nM [IC50]

PubMed

Title	Date	PubMed
Influence of CYP2D6 genotype on the disposition of the enantiomers of venlafaxine and its major metabolites in postmortem femoral blood.	2012-01-10	21840145

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:30:25 GMT 2025` Edited by `admin` on `Mon Mar 31 21:30:25 GMT 2025`
Record UNII	19V5EX4E8B
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

N-DESMETHYLVENLAFAXINE

Common Name

English

VENLAFAXINE RELATED COMPOUND A

Preferred Name

English

VENLAFAXINE RELATED COMPOUND A [USP IMPURITY]

Common Name

English

CYCLOHEXANOL, 1-(1-(4-METHOXYPHENYL)-2-(METHYLAMINO)ETHYL)-

Systematic Name

English

VENLAFAXINE HYDROCHLORIDE IMPURITY D [EP IMPURITY]

Common Name

English

VENLAFAXINE RELATED COMPOUND A [USP-RS]

Common Name

English

NORVENLAFAXINE

Common Name

English

1-((1RS)-1-(4-METHOXYPHENYL)-2-(METHYLAMINO)ETHYL)CYCLOHEXANOL

Systematic Name

English

Code System Code Type Description

RS_ITEM_NUM

1711279