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Details

Stereochemistry ABSOLUTE
Molecular Formula C25H34F2O5
Molecular Weight 452.5313
Optical Activity ( + )
Defined Stereocenters 4 / 4
E/Z Centers 2
Charge 0

SHOW SMILES / InChI
Structure of Tafluprost

SMILES

CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\C(F)(F)COC2=CC=CC=C2

InChI

InChIKey=WSNODXPBBALQOF-VEJSHDCNSA-N
InChI=1S/C25H34F2O5/c1-18(2)32-24(30)13-9-4-3-8-12-20-21(23(29)16-22(20)28)14-15-25(26,27)17-31-19-10-6-5-7-11-19/h3,5-8,10-11,14-15,18,20-23,28-29H,4,9,12-13,16-17H2,1-2H3/b8-3-,15-14+/t20-,21-,22+,23-/m1/s1

HIDE SMILES / InChI
Molecular Formula C25H34F2O5
Molecular Weight 452.5313
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 2
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 17:53:04 UTC 2023
Edited
by admin
on Sat Dec 16 17:53:04 UTC 2023
Record UNII
1O6WQ6T7G3
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Tafluprost
DASH   INCI   INN   JAN   MART.   MI   ORANGE BOOK   USAN   VANDF   WHO-DD  
INCI   INN   USAN  
Official Name English
5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-, 1-methylethyl ester, (5Z)-
Systematic Name English
TAFLUPROST [USAN]
Common Name English
AFP-168
Code English
TAFLUPROST [VANDF]
Common Name English
MK-2452
Code English
TAFLUPROST [ORANGE BOOK]
Common Name English
isopropyl (Z)-7-[(1R,2R,3R,5S)-2-[(E)-3,3-difluoro-4-phenoxy-but-1-enyl]-3,5-dihydroxy-cyclopentyl]hept-5-enoate
Systematic Name English
Tafluprost [WHO-DD]
Common Name English
TAFLUPROST [JAN]
Common Name English
TAFLUPROST [MART.]
Common Name English
TAFLUPROST [INCI]
Common Name English
tafluprost [INN]
Common Name English
TAFLUPROST [MI]
Common Name English
Classification Tree Code System Code
WHO-ATC S01EE05
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
NCI_THESAURUS C78568
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
NDF-RT N0000175454
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
WHO-VATC QS01EE05
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
Code System Code Type Description
INN
8374
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
PRIMARY
NCI_THESAURUS
C87385
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
PRIMARY
EPA CompTox
DTXSID40102150
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
PRIMARY
WIKIPEDIA
Tafluprost
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
PRIMARY
MESH
C485333
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
PRIMARY
SMS_ID
100000115886
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
PRIMARY
DRUG BANK
DB08819
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
PRIMARY
IUPHAR
7451
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
PRIMARY
MERCK INDEX
m10430
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
PRIMARY Merck Index
CAS
209860-87-7
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
PRIMARY
DRUG CENTRAL
4229
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
PRIMARY
ChEMBL
CHEMBL1963683
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
PRIMARY
DAILYMED
1O6WQ6T7G3
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
PRIMARY
LACTMED
Tafluprost
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
PRIMARY
NDF-RT
N0000009526
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
PRIMARY Increased Prostaglandin Activity [PE]
RXCUI
1244607
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
PRIMARY RxNorm
USAN
XX-62
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
PRIMARY
FDA UNII
1O6WQ6T7G3
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
PRIMARY
EVMPD
SUB30776
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
PRIMARY
PUBCHEM
9868491
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
PRIMARY
CHEBI
66899
Created by admin on Sat Dec 16 17:53:05 UTC 2023 , Edited by admin on Sat Dec 16 17:53:05 UTC 2023
PRIMARY
Related Record Type Details
Structure of Tafluprost acid
METABOLITE ACTIVE -> PRODRUG
Structure of (1R,2R,3R,5S)-2-((1E)-3,3-DIFLUORO-4-PHENOXY-1-BUTEN-1-YL)-3,5-DIHYDROXYCYCLOPENTANEPROPANOIC ACID
METABOLITE -> PARENT
Related Record Type Details
Structure of TF-Diol
IMPURITY -> PARENT
Related Record Type Details
Structure of Tafluprost acid
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