TYROSINE-PROTEIN KINASE LYN

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 02:57:00 GMT 2025` Edited by `admin` on `Wed Apr 02 02:57:00 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	20P44G34E0
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TYROSINE-PROTEIN KINASE LYN

Common Name

English

JTK8

Preferred Name

English

P56LYN

Common Name

English

V-YES-1 YAMAGUCHI SARCOMA VIRAL RELATED ONCOGENE HOMOLOG

Common Name

English

LCK/YES-RELATED NOVEL PROTEIN TYROSINE KINASE

Common Name

English

LYN

Common Name

English

P53LYN

Common Name

English

Code System Code Type Description

UNIPROT

P07948

Created by admin on Wed Apr 02 02:57:00 GMT 2025 , Edited by admin on Wed Apr 02 02:57:00 GMT 2025

PRIMARY

FDA UNII

20P44G34E0

Created by admin on Wed Apr 02 02:57:00 GMT 2025 , Edited by admin on Wed Apr 02 02:57:00 GMT 2025

PRIMARY

Related Record Type Details


					M59NC4E26P

MASITINIB

INHIBITOR -> TARGET


					25U4N985O2

PF-05089771

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					3MAE0MXI6K

TG-100435

INHIBITOR -> TARGET

Qualification:

Ki

Amount:

Structural Modifications

Modification Type	Location Site	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_10] [1_12] [1_227]	DEXFOSFOSERINE	VI4F0K069V
AMINO ACID SUBSTITUTION	[1_507]	TYROSINE O-PHOSPHATE	2R86C98KDX
AMINO ACID SUBSTITUTION	[1_396]	TYROSINE O-PHOSPHATE	2R86C98KDX
AMINO ACID SUBSTITUTION	[1_192] [1_305] [1_315] [1_459] [1_472]	TYROSINE O-PHOSPHATE	2R86C98KDX

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL