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Details

Stereochemistry ABSOLUTE
Molecular Formula C16H17N3O5S.H2O
Molecular Weight 381.404
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CEFADROXIL

SMILES

O.[H][C@]12SCC(C)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)C3=CC=C(O)C=C3)C(O)=O

InChI

InChIKey=NBFNMSULHIODTC-CYJZLJNKSA-N
InChI=1S/C16H17N3O5S.H2O/c1-7-6-25-15-11(14(22)19(15)12(7)16(23)24)18-13(21)10(17)8-2-4-9(20)5-3-8;/h2-5,10-11,15,20H,6,17H2,1H3,(H,18,21)(H,23,24);1H2/t10-,11-,15-;/m1./s1

HIDE SMILES / InChI
Molecular Formula C16H17N3O5S
Molecular Weight 363.388
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 3 / 3
E/Z Centers 0
Optical Activity UNSPECIFIED
Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
123738
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:07:32 UTC 2023
Edited
by admin
on Fri Dec 15 15:07:32 UTC 2023
Record UNII
280111G160
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CEFADROXIL
GREEN BOOK   USAN   USP   USP-RS   VANDF  
USAN  
Official Name English
CEFADROXIL (AS MONOHYDRATE)
Common Name English
(6R,7R)-7-((R)-2-AMINO-2-(P-HYDROXYPHENYL)ACETAMIDO)-3-METHYL-8-OXO-5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID MONOHYDRATE
Common Name English
CEFADROXIL [GREEN BOOK]
Common Name English
NSC-756664
Code English
5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID, 7-((AMINO(4-HYDROXYPHENYL)ACETYL)AMINO)-3-METHYL-8-OXO-, MONOHYDRATE, (6R-(6.ALPHA.,7.BETA.(R*)))
Common Name English
BL-S578
Code English
DURACEF
Brand Name English
CEFADROXIL MONOHYDRATE [EP MONOGRAPH]
Common Name English
CEFADROXIL [USP-RS]
Common Name English
MJF 11567-3
Code English
CEFADROXIL MONOHYDRATE
EP   MI   VANDF   WHO-DD  
Common Name English
Cefadroxil monohydrate [WHO-DD]
Common Name English
DURICEF
Brand Name English
CEFADROXIL [USAN]
Common Name English
CEFADROXIL [USP MONOGRAPH]
Common Name English
CEFADROXIL HYDRATE
Common Name English
CEFADROXIL [VANDF]
Common Name English
CEFADROXIL MONOHYDRATE [MI]
Common Name English
CEFADROXIL MONOHYDRATE [VANDF]
Common Name English
MJF-11567-3
Code English
Classification Tree Code System Code
NCI_THESAURUS C357
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
WHO-VATC QJ01DB05
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
CFR 21 CFR 520.314
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
LIVERTOX NBK548358
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
NDF-RT N0000175488
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
LIVERTOX NBK548666
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
WHO-ATC J01DB05
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
Code System Code Type Description
RXCUI
204175
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
PRIMARY
DRUG CENTRAL
526
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
PRIMARY
DAILYMED
280111G160
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
PRIMARY
NCI_THESAURUS
C28912
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
PRIMARY
MESH
D002434
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
PRIMARY
LACTMED
Cefadroxil
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
PRIMARY
SMS_ID
100000092290
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
PRIMARY
CHEBI
53667
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
PRIMARY
MERCK INDEX
m3185
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
PRIMARY Merck Index
RXCUI
407888
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
ALTERNATIVE
WIKIPEDIA
Cefadroxil
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
PRIMARY
RS_ITEM_NUM
1097104
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
PRIMARY
ChEMBL
CHEMBL1644
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
PRIMARY
NSC
756664
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
PRIMARY
EPA CompTox
DTXSID80904597
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
PRIMARY
CAS
66592-87-8
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
PRIMARY
FDA UNII
280111G160
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
PRIMARY
CHEBI
3479
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
PRIMARY
EVMPD
SUB13272MIG
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
PRIMARY
DRUG BANK
DB01140
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
PRIMARY
PUBCHEM
47964
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
PRIMARY
RXCUI
2177
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
ALTERNATIVE
IUPHAR
4831
Created by admin on Fri Dec 15 15:07:32 UTC 2023 , Edited by admin on Fri Dec 15 15:07:32 UTC 2023
PRIMARY
Related Record Type Details
OAT-3
TRANSPORTER -> INHIBITOR
Structure of CEFADROXIL ANHYDROUS
PARENT -> SALT/SOLVATE
Structure of CEFADROXIL ANHYDROUS
ANHYDROUS->SOLVATE
Structure of CEFADROXIL ANHYDROUS
BASIS OF STRENGTH->SUBSTANCE
calculated on the anhydrous basis
ASSAY (HPLC)
USP
Structure of CEFADROXIL ANHYDROUS
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
EP
OAT-1
TRANSPORTER -> INHIBITOR
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
BINDING
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IMPURITY -> PARENT
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Structure of (6R,7R)-7-((R)-2-AMINO-2-(4-((ETHOXYCARBONYL)OXY)PHENYL)ACETAMIDO)-3-METHYL-8-OXO-5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID
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IMPURITY -> PARENT
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IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Related Record Type Details
Structure of CEFADROXIL ANHYDROUS
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Volume of Distribution PHARMACOKINETIC
Biological Half-life PHARMACOKINETIC
NIH
NCATS
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