GUADECITABINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C18H24N9O10P
Molecular Weight	557.4112
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of GUADECITABINE

Structure Search

SMILES

NC1=NC(=O)C2=C(N1)N(C=N2)[C@H]3C[C@H](O)[C@@H](COP(O)(=O)O[C@H]4C[C@@H](O[C@@H]4CO)N5C=NC(N)=NC5=O)O3

InChI

InChIKey=GUWXKKAWLCENJA-WGWHJZDNSA-N

InChI=1S/C18H24N9O10P/c19-16-22-6-27(18(31)25-16)12-2-8(9(3-28)35-12)37-38(32,33)34-4-10-7(29)1-11(36-10)26-5-21-13-14(26)23-17(20)24-15(13)30/h5-12,28-29H,1-4H2,(H,32,33)(H2,19,25,31)(H3,20,23,24,30)/t7-,8-,9+,10+,11+,12+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C18H24N9O10P
Molecular Weight	557.4112
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	6 / 6
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:46:44 UTC 2023` Edited by `admin` on `Fri Dec 15 19:46:44 UTC 2023`
Record UNII	2KT4YN1DP7
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

GUADECITABINE

Official Name

English

Guadecitabine [WHO-DD]

Common Name

English

((2R,3S,5R)-5-(2-AMINO-6-OXO-1,6-DIHYDRO-9H-PURIN-9-YL)-3- HYDROXYTETRAHYDROFURAN-2-YL)METHYL (2R,3S,5R)-5-(4-AMINO-2-OXO-1 ,3,5-TRIAZIN-1(2H)YL)- 2-(HYDROXYMETHYL)TETRAHYDROFURAN-3-YL HYDROGEN PHOSPHATE

Systematic Name

English

SGI-110 FREE ACID

Code

English

SGI-110

Code

English

GUADECITABINE [USAN]

Common Name

English

guadecitabine [INN]

Common Name

English

GUANOSINE, 2'-DEOXY-5-AZACYTIDYLYL-(3'-5')-2'-DEOXY-

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

627818

Created by admin on Fri Dec 15 19:46:44 UTC 2023 , Edited by admin on Fri Dec 15 19:46:44 UTC 2023

NCI_THESAURUS

C2083

Created by admin on Fri Dec 15 19:46:44 UTC 2023 , Edited by admin on Fri Dec 15 19:46:44 UTC 2023

FDA ORPHAN DRUG

492515

Created by admin on Fri Dec 15 19:46:44 UTC 2023 , Edited by admin on Fri Dec 15 19:46:44 UTC 2023

Code System Code Type Description

DRUG BANK

DB11918

Created by admin on Fri Dec 15 19:46:44 UTC 2023 , Edited by admin on Fri Dec 15 19:46:44 UTC 2023

PRIMARY

FDA UNII

2KT4YN1DP7

Created by admin on Fri Dec 15 19:46:44 UTC 2023 , Edited by admin on Fri Dec 15 19:46:44 UTC 2023

PRIMARY

NCI_THESAURUS

C95209

Created by admin on Fri Dec 15 19:46:44 UTC 2023 , Edited by admin on Fri Dec 15 19:46:44 UTC 2023

PRIMARY

EVMPD

SUB177922

Created by admin on Fri Dec 15 19:46:44 UTC 2023 , Edited by admin on Fri Dec 15 19:46:44 UTC 2023

PRIMARY

SMS_ID

100000163603

Created by admin on Fri Dec 15 19:46:44 UTC 2023 , Edited by admin on Fri Dec 15 19:46:44 UTC 2023

PRIMARY

USAN

AB-42

Created by admin on Fri Dec 15 19:46:44 UTC 2023 , Edited by admin on Fri Dec 15 19:46:44 UTC 2023

PRIMARY

ChEMBL

CHEMBL3544916

Created by admin on Fri Dec 15 19:46:44 UTC 2023 , Edited by admin on Fri Dec 15 19:46:44 UTC 2023

PRIMARY

CAS

929901-49-5

Created by admin on Fri Dec 15 19:46:44 UTC 2023 , Edited by admin on Fri Dec 15 19:46:44 UTC 2023

PRIMARY

INN

10102

Created by admin on Fri Dec 15 19:46:44 UTC 2023 , Edited by admin on Fri Dec 15 19:46:44 UTC 2023

PRIMARY

PUBCHEM

135564655

Created by admin on Fri Dec 15 19:46:44 UTC 2023 , Edited by admin on Fri Dec 15 19:46:44 UTC 2023

PRIMARY

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