Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C10H14N2O6 |
| Molecular Weight | 258.228 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C=CC(=O)NC2=O
InChI
InChIKey=SXUXMRMBWZCMEN-ZOQUXTDFSA-N
InChI=1S/C10H14N2O6/c1-17-8-7(15)5(4-13)18-9(8)12-3-2-6(14)11-10(12)16/h2-3,5,7-9,13,15H,4H2,1H3,(H,11,14,16)/t5-,7-,8-,9-/m1/s1
| Molecular Formula | C10H14N2O6 |
| Molecular Weight | 258.228 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: 2'-O-methyluridine hydrolase (E. coli) Sources: https://www.ncbi.nlm.nih.gov/pubmed/30405065 |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Distinct Modified Nucleosides in tRNATrp from the Hyperthermophilic Archaeon Thermococcus kodakarensis and Requirement of tRNA m2G10/m2 2G10 Methyltransferase (Archaeal Trm11) for Survival at High Temperatures. | 2019-11-01 |
|
| Structural and Energetic Effects of O2'-Ribose Methylation of Protonated Pyrimidine Nucleosides. | 2019-11 |
|
| Identification of a 2'-O-Methyluridine Nucleoside Hydrolase Using the Metagenomic Libraries. | 2018-11-07 |
|
| Osmium Tag for Post-transcriptionally Modified RNA. | 2018-08-06 |
|
| New nucleoside hydrolase with transribosylation activity from Agromyces sp. MM-1 and its application for enzymatic synthesis of 2'-O-methylribonucleosides. | 2018-01 |
|
| Enzymatic synthesis of 2'-O-methylribonucleosides with a nucleoside hydrolase family enzyme from Lactobacillus buchneri LBK78. | 2017-06 |
|
| A novel nucleoside hydrolase from Lactobacillus buchneri LBK78 catalyzing hydrolysis of 2'-O-methylribonucleosides. | 2016-08 |
|
| ADME studies of [5-(3)H]-2'-O-methyluridine nucleoside in mice: a building block in siRNA therapeutics. | 2016-02 |
|
| Single methylation of 23S rRNA triggers late steps of 50S ribosomal subunit assembly. | 2015-08-25 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 23:16:31 GMT 2025
by
admin
on
Mon Mar 31 23:16:31 GMT 2025
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| Record UNII |
399VZB6TMB
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| Record Status |
Validated (UNII)
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| Record Version |
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