Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Wed Apr 02 14:30:21 GMT 2025
by
admin
on
Wed Apr 02 14:30:21 GMT 2025
|
| Protein Type | RECEPTOR |
| Protein Sub Type | GROWTH FACTOR RECEPTOR |
| Sequence Origin | HUMAN |
| Sequence Type | COMPLETE |
| Record UNII |
3FJ2AHL47Q
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
3FJ2AHL47Q
Created by
admin on Wed Apr 02 14:30:21 GMT 2025 , Edited by admin on Wed Apr 02 14:30:21 GMT 2025
|
PRIMARY |
| From | To |
|---|---|
| 1_7 | 1_34 |
| 1_133 | 1_163 |
| 1_166 | 1_175 |
| 1_170 | 1_183 |
| 1_191 | 1_199 |
| 1_195 | 1_207 |
| 1_208 | 1_216 |
| 1_212 | 1_224 |
| 1_227 | 1_236 |
| 1_240 | 1_267 |
| 1_271 | 1_283 |
| 1_287 | 1_302 |
| 1_305 | 1_309 |
| 1_313 | 1_338 |
| 1_446 | 1_475 |
| 1_482 | 1_491 |
| 1_486 | 1_499 |
| 1_502 | 1_511 |
| 1_515 | 1_531 |
| 1_534 | 1_547 |
| 1_538 | 1_555 |
| 1_558 | 1_567 |
| 1_571 | 1_593 |
| 1_596 | 1_604 |
| 1_600 | 1_612 |
| Glycosylation Link Type | Site |
|---|---|
| N | 1_32 |
| N | 1_49 |
| N | 1_104 |
| N | 1_151 |
| N | 1_172 |
| N | 1_328 |
| N | 1_337 |
| N | 1_389 |
| N | 1_420 |
| N | 1_504 |
| N | 1_544 |
| N | 1_579 |
| N | 1_599 |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
TARGET -> INHIBITOR |
Approved for treatment of EGFR EXON 20 insertions mutations in NSLC
|
||
|
|
TARGET -> INHIBITOR |
Approved for treatment of EGFR EXON 20 insertions mutations in NSLC
|
Structural Modifications
| Modification Type | Location Site | Location Type | Residue Modified | Extent | Fragment Name | Fragment Approval |
|---|---|---|---|---|---|---|
| AMINO ACID SUBSTITUTION | [1_654] | THREONINE PHOSPHATE | 3L4WX7B1EI | |||
| AMINO ACID SUBSTITUTION | [1_977] [1_995] [1_1071] [1_1089] [1_1151] [1_1176] | TYROSINE O-PHOSPHATE | 2R86C98KDX | |||
| AMINO ACID SUBSTITUTION | [1_1178] | TILARGININE | 27JT06E6GR |
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| Molecular Formula | CHEMICAL |
|
||||
| MOL_WEIGHT | CHEMICAL |
|