NUCLEAR RECEPTOR ROR-GAMMA

Substance Class	Protein Created by `admin` on `Tue Apr 01 18:16:32 GMT 2025` Edited by `admin` on `Tue Apr 01 18:16:32 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	3HLK2F1I2R
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

Common Name

English

NUCLEAR RECEPTOR ROR-GAMMA ISOFORM 1

Preferred Name

English

ROR?

Common Name

English

RAR-RELATED ORPHAN RECEPTOR C

Common Name

English

RETINOID-RELATED ORPHAN RECEPTOR-GAMMA

Common Name

English

Code System Code Type Description

FDA UNII

3HLK2F1I2R

Created by admin on Tue Apr 01 18:16:32 GMT 2025 , Edited by admin on Tue Apr 01 18:16:32 GMT 2025

PRIMARY

UNIPROT

P51449

Created by admin on Tue Apr 01 18:16:32 GMT 2025 , Edited by admin on Tue Apr 01 18:16:32 GMT 2025

PRIMARY

Linkage Type	Residue Index
COORDINATION COMPOUND	1_31	1_34	1_48	1_51
COORDINATION COMPOUND	1_67	1_73	1_83	1_86

Related Record Type Details


					LPN433P0EA

AGONIST -> TARGET


					JVS2L11ROA

JTE-151

INHIBITOR -> TARGET

Qualification:

EC50

Amount:


					L49V5G013I

INVERSE AGONIST->TARGET


					U2GR892E11

INHIBITOR -> TARGET

Amount:

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_67] [1_73] [1_83] [1_86]	SITE_SPECIFIC			C4-TYPE ZINC FINGER	C56TF4V7OP
AMINO_ACID_SUBSTITUTION	[1_31] [1_34] [1_48] [1_51]	SITE_SPECIFIC			C4-TYPE ZINC FINGER	C56TF4V7OP

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL
Molecular Formula	CHEMICAL