NUCLEAR RECEPTOR SUBFAMILY 1 GROUP I MEMBER 3

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 02:47:16 GMT 2025` Edited by `admin` on `Wed Apr 02 02:47:16 GMT 2025`
Protein Type	RECEPTOR
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	438XLITDI3
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NUCLEAR RECEPTOR SUBFAMILY 1 GROUP I MEMBER 3

Common Name

English

CAR

Preferred Name

English

CONSTITUTIVE ACTIVATOR OF RETINOID RESPONSE

Common Name

English

NR1I3

Common Name

English

CONSTITUTIVE ANDROSTANE RECEPTOR

Common Name

English

ORPHAN NUCLEAR RECEPTOR MB67

Common Name

English

CONSTITUTIVE ACTIVE RESPONSE

Common Name

English

Code System Code Type Description

FDA UNII

438XLITDI3

Created by admin on Wed Apr 02 02:47:16 GMT 2025 , Edited by admin on Wed Apr 02 02:47:16 GMT 2025

PRIMARY

Linkage Type	Residue Index
COORDINATION COMPOUND	1_47	1_53	1_63	1_66
COORDINATION COMPOUND	1_11	1_14	1_28	1_31

Related Record Type Details


					0GEI24LG0J

CHENODIOL

AGONIST -> TARGET

Interaction Type:

INHIBITOR

Qualification:

EC50

Amount:


					459AG36T1B

PRASTERONE

ACTIVATOR -> TARGET

Interaction Type:

ACTIVATOR

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_11] [1_14] [1_28] [1_31]	SITE_SPECIFIC	C4-TYPE ZINC FINGER	C56TF4V7OP
AMINO ACID SUBSTITUTION	[1_38]		THREONINE PHOSPHATE	3L4WX7B1EI
AMINO_ACID_SUBSTITUTION	[1_47] [1_53] [1_63] [1_66]	SITE_SPECIFIC	C4-TYPE ZINC FINGER	C56TF4V7OP

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL