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Approval Year

Unknown
86413
Substance Class Mixture
Created
by admin
on Fri Dec 15 15:38:19 UTC 2023
Edited
by admin
on Fri Dec 15 15:38:19 UTC 2023
Record UNII
4W0459ZA4V
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CEFPROZIL
ORANGE BOOK   USAN   USP   USP-RS   VANDF  
USAN  
Official Name English
CEFPROZIL [VANDF]
Common Name English
NSC-759099
Code English
5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID, 7-((AMINO(4-HYDROXYPHENYL)ACETYL)AMINO)-8-OXO-3-(1-PROPENYL)-, MONOHYDRATE, (6R-(6.ALPHA.,7.BETA.(R*)))-
Common Name English
Cefprozil monohydrate [WHO-DD]
Common Name English
CEFPROZIL MONOHYDRATE [EP MONOGRAPH]
Common Name English
CEFPROZIL MONOHYDRATE
EP   MI   WHO-DD  
Common Name English
CEFPROZIL [USAN]
Common Name English
CEFPROZIL MONOHYDRATE [MI]
Common Name English
CEFPROZIL [USP MONOGRAPH]
Common Name English
CEFPROZIL [USP-RS]
Common Name English
CEFPROZIL [ORANGE BOOK]
Common Name English
BMY-28100-03-800
Code English
5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID, 7-(((2R)-2-AMINO-2-(4-HYDROXYPHENYL)ACETYL)AMINO)-8-OXO-3-(1-PROPEN-1-YL)-, HYDRATE (1:1), (6R,7R)-
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C357
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
NDF-RT N0000011161
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
WHO-VATC QJ01DC10
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
NDF-RT N0000175488
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
NDF-RT N0000011161
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
NDF-RT N0000011161
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
NDF-RT N0000011161
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
LIVERTOX NBK548358
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
NDF-RT N0000011161
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
WHO-ATC J01DC10
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
NDF-RT N0000011161
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
NDF-RT N0000011161
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
LIVERTOX NBK548666
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
NDF-RT N0000011161
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
NDF-RT N0000011161
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
NDF-RT N0000011161
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
NDF-RT N0000011161
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
NDF-RT N0000011161
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
Code System Code Type Description
RXCUI
19552
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
PRIMARY RxNorm
DRUG BANK
DB01150
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
PRIMARY
ChEMBL
CHEMBL3301800
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
PRIMARY
RS_ITEM_NUM
1098062
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
PRIMARY
MERCK INDEX
m3213
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
PRIMARY Merck Index
CHEBI
3506
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
PRIMARY
NSC
759099
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
PRIMARY
USAN
Z-66
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
PRIMARY
DRUG CENTRAL
556
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
PRIMARY
CAS
121123-17-9
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
PRIMARY
EVMPD
SUB21728
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
PRIMARY
LACTMED
Cefprozil
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
PRIMARY
EPA CompTox
DTXSID3046085
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
PRIMARY
NCI_THESAURUS
C28917
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
PRIMARY
DAILYMED
4W0459ZA4V
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
PRIMARY
MESH
C052018
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
PRIMARY
FDA UNII
4W0459ZA4V
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
PRIMARY
WIKIPEDIA
CEFPROZIL
Created by admin on Fri Dec 15 15:38:19 UTC 2023 , Edited by admin on Fri Dec 15 15:38:19 UTC 2023
PRIMARY
All of the following components must be present:
Structure of CEFPROZIL, (Z)-
Structure of CEFPROZIL, (E)-
Related Record Type Details
CEFPROZIL ANHYDROUS
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
EP
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
BINDING
CEFPROZIL ANHYDROUS
ANHYDROUS->SOLVATE
CEFPROZIL ANHYDROUS
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
USP
Related Record Type Details
Structure of 2-HYDROXYETHYL (2R)-2-AMINO-2-(4-HYDROXYPHENYL)ACETATE
IMPURITY -> PARENT
3-(AMINOMETHYLENE)-6-(4-HYDROXYPHENYL)PIPERAZINE-2,5-DIONE
IMPURITY -> PARENT
Structure of 4-HYDROXYPHENYLGLYCINE, D-(-)-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 3-((2R,5R)-5-ETHYL-7-OXO-1,2,5,7-TETRAHYDRO-4H-FURO(3,4-D)(1,3)THIAZIN-2-YL)-6-(4-HYDROXYPHENYL)PIPERAZINE-2,5-DIONE
IMPURITY -> PARENT
Structure of CEFADROXIL ANHYDROUS
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of CEFPROZIL AMIDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 3-(AMINOMETHYLENE)-6-(4-HYDROXYPHENYL)PIPERAZINE-2,5-DIONE, (E)-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of OPEN RING CEFPROZIL, (Z)-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of N-((2R)-2-AMINO-2-(4-HYDROXYPHENYL)ACETYL) CEFPROZIL, (E)-
IMPURITY -> PARENT
Structure of CEFPROZIL DIMER
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of O-((2R)-2-AMINO-2-(4-HYDROXYPHENYL)ACETYL)CEFPROZIL, (Z)-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of OPEN RING CEFPROZIL, (E)-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of OPEN RING CEFPROZIL, (Z)-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of CEFADROXIL ANHYDROUS
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of N-((2R)-2-AMINO-2-(4-HYDROXYPHENYL)ACETYL) CEFPROZIL, (Z)-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of (6R,7R)-7-((R)-2-AMINO-2-(4-HYDROXYPHENYL)ACETAMIDO)-8-OXO-3-((Z)-PROP-1-EN-1-YL)-5-THIA-1-AZABICYCLO(4.2.0)OCT-3-ENE-2-CARBOXYLIC ACID
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 7-AMINO-8-OXO-3-((1Z)-PROP-1-ENYL)-5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID, (6R,7R)-
IMPURITY -> PARENT
For the calculation of content, multiply the peak area by 2.3
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of O-ETHOXYCARBONYL CEFPROZIL, (E)-
IMPURITY -> PARENT
Structure of 7-AMINO-8-OXO-3-((1E)-PROP-1-ENYL)-5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID, (6R,7R)-
IMPURITY -> PARENT
The limit for the sum of Cefprozil related compound D (Z)-isomer and Cefprozil related compound D (E)-isomer is 0.3%.
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of METHOXYCEFADROXIL
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of O-ETHOXYCARBONYL CEFPROZIL, (Z)-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
CEFPROZIL ANHYDROUS
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Volume of Distribution PHARMACOKINETIC
Biological Half-life PHARMACOKINETIC
Definition References
NIH
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