IMIPENEM

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C12H17N3O4S.H2O
Molecular Weight	317.361
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of IMIPENEM

Structure Search

SMILES

O.[H][C@]12CC(SCCNC=N)=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O

InChI

InChIKey=GSOSVVULSKVSLQ-JJVRHELESA-N

InChI=1S/C12H17N3O4S.H2O/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17;/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19);1H2/t6-,7-,9-;/m1./s1

HIDE SMILES / InChI

Molecular Formula	H2O
Molecular Weight	18.0153
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C12H17N3O4S
Molecular Weight	299.346
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:15:40 UTC 2023` Edited by `admin` on `Fri Dec 15 15:15:40 UTC 2023`
Record UNII	71OTZ9ZE0A
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

IMIPENEM

Official Name

English

MK-0787

Code

English

IMIPENEM [ORANGE BOOK]

Common Name

English

IMIPENEM MONOHYDRATE [USP-RS]

Common Name

English

PRIMAXIN COMPONENT IMIPENEM

Common Name

English

IMIPENEM COMPONENT OF PRIMAXIN

Common Name

English

IMIPENEM [MART.]

Common Name

English

NSC-759901

Code

English

IMIPENEM HYDRATE [JAN]

Common Name

English

IMIPENEM [VANDF]

Common Name

English

IMIPENEM MONOHYDRATE [MI]

Common Name

English

IMIPENEM [USP MONOGRAPH]

Common Name

English

IMIPENEM MONOHYDRATE (H2O)

Common Name

English

IMIPENEM HYDRATE

Common Name

English

IMIPENEM COMPONENT OF RECARBRIO

Brand Name

English

Imipenem monohydrate [WHO-DD]

Common Name

English

IMIPENEM MONOHYDRATE

Common Name

English

IMIPENEM [USAN]

Common Name

English

RECARBRIO COMPONENT IMIPENEM

Brand Name

English

IMIPENEM MONOHYDRATE [EP MONOGRAPH]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C260

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

WHO-ATC

J01DH51

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

NDF-RT

N0000175496

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

WHO-ESSENTIAL MEDICINES LIST

6.2.1 (IMI/CIL)

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

WHO-VATC

QJ01DH51

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

LIVERTOX

NBK548708

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

Code System Code Type Description

LACTMED

Imipenem and Cilastatin

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

PRIMARY

NSC

759901

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

PRIMARY

CHEBI

471744

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

PRIMARY

MESH

D015378

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

PRIMARY

ChEMBL

CHEMBL148

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

PRIMARY

USAN

S-2

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

PRIMARY

EVMPD

SUB21472

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

PRIMARY

DRUG CENTRAL

1426

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

PRIMARY

DRUG BANK

DB01598

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

PRIMARY

EPA CompTox

DTXSID00873392

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

PRIMARY

RS_ITEM_NUM

1337809

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

PRIMARY

DAILYMED

71OTZ9ZE0A

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

PRIMARY

NCI_THESAURUS

C570

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

PRIMARY

CAS

74431-23-5

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

PRIMARY

SMS_ID

100000091637

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

PRIMARY

WIKIPEDIA

IMIPENEM

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

PRIMARY

PUBCHEM

5282372

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

PRIMARY

FDA UNII

71OTZ9ZE0A

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

PRIMARY

RXCUI

2184135

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

ALTERNATIVE

MERCK INDEX

m6231

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

PRIMARY

Merck Index

CHEBI

51799

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

PRIMARY

RXCUI

5690

Created by admin on Fri Dec 15 15:15:40 UTC 2023 , Edited by admin on Fri Dec 15 15:15:40 UTC 2023

PRIMARY

RxNorm

Related Record Type Details


					Q20IM7HE75

IMIPENEM ANHYDROUS

PARENT -> SALT/SOLVATE


					PLW8GC3JKC

OXA-48 (Beta-lactamase)

ENZYME->SUBSTRATE

Comments:

Leads to resistance to the antibiotic.

Amount:


					Q20IM7HE75

IMIPENEM ANHYDROUS

ANHYDROUS->SOLVATE


					Q20IM7HE75

IMIPENEM ANHYDROUS

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (HPLC)

Qualification:

USP

Amount:


					Q20IM7HE75

IMIPENEM ANHYDROUS

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (HPLC)

Qualification:

EP

Amount:

Related Record Type Details


					WMW5I5964P

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					93B2M7CLL0

IMIPENEMOIC ACID

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Related Record Type Details


					Q20IM7HE75

IMIPENEM ANHYDROUS

ACTIVE MOIETY