U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry RACEMIC
Molecular Formula C11H15BrClO3PS
Molecular Weight 373.631
Optical Activity ( + / - )
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PROFENOFOS

SMILES

CCCSP(=O)(OCC)OC1=CC=C(Br)C=C1Cl

InChI

InChIKey=QYMMJNLHFKGANY-UHFFFAOYSA-N
InChI=1S/C11H15BrClO3PS/c1-3-7-18-17(14,15-4-2)16-11-6-5-9(12)8-10(11)13/h5-6,8H,3-4,7H2,1-2H3

HIDE SMILES / InChI
Molecular Formula C11H15BrClO3PS
Molecular Weight 373.631
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
149124
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:44:40 GMT 2025
Edited
by admin
on Mon Mar 31 18:44:40 GMT 2025
Record UNII
7J04O7BS4W
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PROFENOFOS
HSDB   ISO   MI  
Common Name English
CURACRON
Preferred Name English
PROFENOFOS [HSDB]
Common Name English
CGA-15324
Code English
PROFENOFOS [MI]
Common Name English
SELECRON
Brand Name English
PROFENOFOS [ISO]
Common Name English
(RS)-(O-4-BROMO-2-CHLOROPHENYL O-ETHYL S-PROPYL PHOSPHOROTHIOATE)
Common Name English
OMS-2004
Code English
O-(4-BROMO-2-CHLOROPHENYL) O-ETHYL S-PROPYL PHOSPHOROTHIOATE
Systematic Name English
PROFENOPHOS
Brand Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 111401
Created by admin on Mon Mar 31 18:44:40 GMT 2025 , Edited by admin on Mon Mar 31 18:44:40 GMT 2025
Code System Code Type Description
HSDB
6992
Created by admin on Mon Mar 31 18:44:40 GMT 2025 , Edited by admin on Mon Mar 31 18:44:40 GMT 2025
PRIMARY
ALANWOOD
profenofos
Created by admin on Mon Mar 31 18:44:40 GMT 2025 , Edited by admin on Mon Mar 31 18:44:40 GMT 2025
PRIMARY
FDA UNII
7J04O7BS4W
Created by admin on Mon Mar 31 18:44:40 GMT 2025 , Edited by admin on Mon Mar 31 18:44:40 GMT 2025
PRIMARY
PUBCHEM
38779
Created by admin on Mon Mar 31 18:44:40 GMT 2025 , Edited by admin on Mon Mar 31 18:44:40 GMT 2025
PRIMARY
ECHA (EC/EINECS)
255-255-2
Created by admin on Mon Mar 31 18:44:40 GMT 2025 , Edited by admin on Mon Mar 31 18:44:40 GMT 2025
PRIMARY
CHEBI
38845
Created by admin on Mon Mar 31 18:44:40 GMT 2025 , Edited by admin on Mon Mar 31 18:44:40 GMT 2025
PRIMARY
MESH
C024273
Created by admin on Mon Mar 31 18:44:40 GMT 2025 , Edited by admin on Mon Mar 31 18:44:40 GMT 2025
PRIMARY
EPA CompTox
DTXSID3032464
Created by admin on Mon Mar 31 18:44:40 GMT 2025 , Edited by admin on Mon Mar 31 18:44:40 GMT 2025
PRIMARY
WIKIPEDIA
Profenofos
Created by admin on Mon Mar 31 18:44:40 GMT 2025 , Edited by admin on Mon Mar 31 18:44:40 GMT 2025
PRIMARY
MERCK INDEX
m9156
Created by admin on Mon Mar 31 18:44:40 GMT 2025 , Edited by admin on Mon Mar 31 18:44:40 GMT 2025
PRIMARY Merck Index
CAS
41198-08-7
Created by admin on Mon Mar 31 18:44:40 GMT 2025 , Edited by admin on Mon Mar 31 18:44:40 GMT 2025
PRIMARY
Related Record Type Details
CYTOCHROME P450 2C8
METABOLIC ENZYME -> INHIBITOR
inhibitions between 59 and 84% were observed with profenofos
CYTOCHROME P450 2C9
METABOLIC ENZYME -> INHIBITOR
CYP2C9 activity was extensively inhibited (more than 90% inhibition) by organophosphorus insecticides profenofos
CYTOCHROME P450 2B6
INNOVATOR->PARENT
Screening of potential CYP2B6 inhibitions illustrates that CYP2B6 activity was extensively inhibited by all tested organophosphate pesticides. Inhibition percentages were 100% with profenofos.
CYTOCHROME P450 1A2
METABOLIC ENZYME -> INHIBITOR
Profenofos inhibited CYP1A1/2 activities more than 90%.
CYTOCHROME P450 1A1
METABOLIC ENZYME -> INHIBITOR
Profenofos inhibited CYP1A1/2 activities more than 90%.
NIH
NCATS
PRIVACY NOTICE
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966