TELOTRISTAT ETHYL

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C27H26ClF3N6O3
Molecular Weight	574.982
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TELOTRISTAT ETHYL

Structure Search

SMILES

CCOC(=O)[C@@H](N)CC1=CC=C(C=C1)C2=CC(O[C@H](C3=C(C=C(Cl)C=C3)N4C=CC(C)=N4)C(F)(F)F)=NC(N)=N2

InChI

InChIKey=MDSQOJYHHZBZKA-GBXCKJPGSA-N

InChI=1S/C27H26ClF3N6O3/c1-3-39-25(38)20(32)12-16-4-6-17(7-5-16)21-14-23(35-26(33)34-21)40-24(27(29,30)31)19-9-8-18(28)13-22(19)37-11-10-15(2)36-37/h4-11,13-14,20,24H,3,12,32H2,1-2H3,(H2,33,34,35)/t20-,24+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C27H26ClF3N6O3
Molecular Weight	574.982
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:47:06 UTC 2023` Edited by `admin` on `Fri Dec 15 19:47:06 UTC 2023`
Record UNII	8G388563M7
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TELOTRISTAT ETHYL

Official Name

English

LX 1606

Code

English

LX-1032

Code

English

TELOTRISTAT ETHYL [USAN]

Common Name

English

Telotristat ethyl [WHO-DD]

Common Name

English

L-PHENYLALANINE, 4-(2-AMINO-6-((1R)-1-(4-CHLORO-2-(3-METHYL-1H-PYRAZOL-1-YL)PHENYL)-2,2,2-TRIFLUOROETHOXY)-4-PRYRIMIDINYL)-, ETHYL ESTER

Common Name

English

LX1606

Code

English

ETHYL 4-(2-AMINO-6-((1R)-1-(4-CHLORO-2-(3-METHYL-1H-PYRAZOL-1-YL)PHENYL)-2,2,2-TRIFLUOROETHOXY)PRYRIMIDIN-4-YL)-L-PHENYLALANINATE

Common Name

English

TELOTRISTAT ETHYL [MI]

Common Name

English

LX 1032

Code

English

LX-1606

Code

English

LX1032

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C471

Created by admin on Fri Dec 15 19:47:06 UTC 2023 , Edited by admin on Fri Dec 15 19:47:06 UTC 2023

Code System Code Type Description

WIKIPEDIA

Telotristat ethyl

Created by admin on Fri Dec 15 19:47:06 UTC 2023 , Edited by admin on Fri Dec 15 19:47:06 UTC 2023

PRIMARY

EVMPD

SUB179123

Created by admin on Fri Dec 15 19:47:06 UTC 2023 , Edited by admin on Fri Dec 15 19:47:06 UTC 2023

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DRUG BANK

DB12095

Created by admin on Fri Dec 15 19:47:06 UTC 2023 , Edited by admin on Fri Dec 15 19:47:06 UTC 2023

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ChEMBL

CHEMBL2105695

Created by admin on Fri Dec 15 19:47:06 UTC 2023 , Edited by admin on Fri Dec 15 19:47:06 UTC 2023

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NCI_THESAURUS

C150126

Created by admin on Fri Dec 15 19:47:06 UTC 2023 , Edited by admin on Fri Dec 15 19:47:06 UTC 2023

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PUBCHEM

25181577

Created by admin on Fri Dec 15 19:47:06 UTC 2023 , Edited by admin on Fri Dec 15 19:47:06 UTC 2023

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EPA CompTox

DTXSID001102271

Created by admin on Fri Dec 15 19:47:06 UTC 2023 , Edited by admin on Fri Dec 15 19:47:06 UTC 2023

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CAS

1033805-22-9

Created by admin on Fri Dec 15 19:47:06 UTC 2023 , Edited by admin on Fri Dec 15 19:47:06 UTC 2023

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FDA UNII

8G388563M7

Created by admin on Fri Dec 15 19:47:06 UTC 2023 , Edited by admin on Fri Dec 15 19:47:06 UTC 2023

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EU-Orphan Drug

EU/3/09/661(POSITIVE)

Created by admin on Fri Dec 15 19:47:06 UTC 2023 , Edited by admin on Fri Dec 15 19:47:06 UTC 2023

PRIMARY

On 30 May 2016, orphan designation (EU/3/09/661) was granted by the European Commission to Ipsen Pharma, France, for (S)-ethyl 2-amino-3-(4-(2-amino-6(-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoate (also known as telotristat etiprate) for the treatment of carcinoid syndrome.

DRUG CENTRAL

5214

Created by admin on Fri Dec 15 19:47:06 UTC 2023 , Edited by admin on Fri Dec 15 19:47:06 UTC 2023

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SMS_ID

100000164628

Created by admin on Fri Dec 15 19:47:06 UTC 2023 , Edited by admin on Fri Dec 15 19:47:06 UTC 2023

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MERCK INDEX

m12015

Created by admin on Fri Dec 15 19:47:06 UTC 2023 , Edited by admin on Fri Dec 15 19:47:06 UTC 2023

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RXCUI

1872441

Created by admin on Fri Dec 15 19:47:06 UTC 2023 , Edited by admin on Fri Dec 15 19:47:06 UTC 2023

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USAN

WW-146

Created by admin on Fri Dec 15 19:47:06 UTC 2023 , Edited by admin on Fri Dec 15 19:47:06 UTC 2023

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DAILYMED

8G388563M7

Created by admin on Fri Dec 15 19:47:06 UTC 2023 , Edited by admin on Fri Dec 15 19:47:06 UTC 2023

PRIMARY

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