BMS-823778 FREE BASE

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	C18H18ClN3O
Molecular Weight	327.808
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)(O)C1=CC=CN2C1=NN=C2C3(CC3)C4=CC=C(Cl)C=C4

InChI

InChIKey=PTIFVLOBVCIMKL-UHFFFAOYSA-N

InChI=1S/C18H18ClN3O/c1-17(2,23)14-4-3-11-22-15(14)20-21-16(22)18(9-10-18)12-5-7-13(19)8-6-12/h3-8,11,23H,9-10H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C18H18ClN3O
Molecular Weight	327.808
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Corticosteroid 11-beta-dehydrogenase isozyme 1 3 Target ID: P28845 Gene ID: 3290.0 Gene Symbol: HSD11B1 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/27169762	Inhibitor 8504

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:01:54 GMT 2025` Edited by `admin` on `Mon Mar 31 21:01:54 GMT 2025`
Record UNII	8JYO8VTR11
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BMS-823778 (FREE BASE)

Preferred Name

English

BMS-823778 FREE BASE

Common Name

English

1,2,4-TRIAZOLO(4,3-A)PYRIDINE-8-METHANOL, 3-(1-(4-CHLOROPHENYL)CYCLOPROPYL)-.ALPHA.,.ALPHA.-DIMETHYL-

Systematic Name

English

Code System Code Type Description

PUBCHEM

42634627

Created by admin on Mon Mar 31 21:01:54 GMT 2025 , Edited by admin on Mon Mar 31 21:01:54 GMT 2025

PRIMARY

CAS

1140897-32-0

Created by admin on Mon Mar 31 21:01:54 GMT 2025 , Edited by admin on Mon Mar 31 21:01:54 GMT 2025

PRIMARY

FDA UNII

8JYO8VTR11

Created by admin on Mon Mar 31 21:01:54 GMT 2025 , Edited by admin on Mon Mar 31 21:01:54 GMT 2025

PRIMARY

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Name	Property Type	Parameters
Biological Half-life	PHARMACOKINETIC	SINGLE DOSE ADMINISTRATION IN HEALTHY CHINESE SUBJECTS

Tmax	PHARMACOKINETIC	IN HEALTHY CHINESE SUBJECTS SINGLE DOSE ADMINISTRATION