Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C30H38N2O2.2ClH |
| Molecular Weight | 531.557 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.Cl.[H][C@]1(CCC2=CC(O)=CC=C2C1)C3=C(C=C(OC)C=C3)N(CC)CC4=CC=C(CCNCC)C=C4
InChI
InChIKey=XGFHYCAZOCBCRQ-FBHGDYMESA-N
InChI=1S/C30H38N2O2.2ClH/c1-4-31-17-16-22-6-8-23(9-7-22)21-32(5-2)30-20-28(34-3)14-15-29(30)26-11-10-25-19-27(33)13-12-24(25)18-26;;/h6-9,12-15,19-20,26,31,33H,4-5,10-11,16-18,21H2,1-3H3;2*1H/t26-;;/m1../s1
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C30H38N2O2 |
| Molecular Weight | 458.6349 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 09:42:51 UTC 2023
by
admin
on
Sat Dec 16 09:42:51 UTC 2023
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| Record UNII |
8NZT0PR8AL
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| Record Status |
Validated (UNII)
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| Record Version |
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-
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Official Name | English | ||
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Preferred Name | English | ||
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Code | English | ||
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Brand Name | English | ||
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Systematic Name | English | ||
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Systematic Name | English | ||
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Common Name | English | ||
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Code | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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C171898
Created by
admin on Sat Dec 16 09:42:51 UTC 2023 , Edited by admin on Sat Dec 16 09:42:51 UTC 2023
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PRIMARY | |||
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GH-121
Created by
admin on Sat Dec 16 09:42:51 UTC 2023 , Edited by admin on Sat Dec 16 09:42:51 UTC 2023
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PRIMARY | |||
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RAD-1901 DIHYDROCHLORIDE
Created by
admin on Sat Dec 16 09:42:51 UTC 2023 , Edited by admin on Sat Dec 16 09:42:51 UTC 2023
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PRIMARY | Description: RAD1901 is an orally available, selective estrogen receptor degrader (SERD) and selective estrogen receptor modulator (SERM), with potential antineoplastic and estrogen-like activities. Upon oral administration of higher doses of RAD1901, this agent acts as a SERD, which binds to the estrogen receptor (ER) and induces a conformational change that results in the degradation of the receptor. This may inhibit the growth and survival of ER-expressing cancer cells. At lower doses of this agent, RAD1901 acts as a SERM and has estrogen-like effects in certain tissues, which can both reduce hot flashes and protect against bone loss. In addition, RAD1901 is able to cross the blood-brain barrier (BBB). (last updated: 5/19/2016).Synonym: RAD1901, RAD-1901, RAD 1901, RAD1901 HCl salt. | ||
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1349723-93-8
Created by
admin on Sat Dec 16 09:42:51 UTC 2023 , Edited by admin on Sat Dec 16 09:42:51 UTC 2023
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SUB184532
Created by
admin on Sat Dec 16 09:42:51 UTC 2023 , Edited by admin on Sat Dec 16 09:42:51 UTC 2023
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8NZT0PR8AL
Created by
admin on Sat Dec 16 09:42:51 UTC 2023 , Edited by admin on Sat Dec 16 09:42:51 UTC 2023
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67479909
Created by
admin on Sat Dec 16 09:42:51 UTC 2023 , Edited by admin on Sat Dec 16 09:42:51 UTC 2023
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100000170508
Created by
admin on Sat Dec 16 09:42:51 UTC 2023 , Edited by admin on Sat Dec 16 09:42:51 UTC 2023
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PRIMARY |
| Related Record | Type | Details | ||
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PARENT -> SALT/SOLVATE |
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| Related Record | Type | Details | ||
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ACTIVE MOIETY |
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