Ro -60-0175 free base

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C11H12ClFN2
Molecular Weight	226.678
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C[C@H](N)CN1C=CC2=CC(F)=C(Cl)C=C12

InChI

InChIKey=XJJZQXUGLLXTHO-ZETCQYMHSA-N

InChI=1S/C11H12ClFN2/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15/h2-5,7H,6,14H2,1H3/t7-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C11H12ClFN2
Molecular Weight	226.678
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Serotonin 2c (5-HT2c) receptor 131 Target ID: CHEMBL225 Sources: https://www.ncbi.nlm.nih.gov/pubmed/12604698\|https://www.ncbi.nlm.nih.gov/pubmed/23301527	Agonist 2752		4.7 nM [EC50]

Substance Class	Chemical Created by `admin` on `Wed Apr 02 15:09:57 GMT 2025` Edited by `admin` on `Wed Apr 02 15:09:57 GMT 2025`
Record UNII	A74GH2T4WD
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Ro -60-0175 free base

Common Name

English

(2S)-1-(6-Chloro-5-fluoro-1H-indol-1-yl)propan-2-amine

Preferred Name

English

(S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine

Systematic Name

English

(?S)-6-Chloro-5-fluoro-?-methyl-1H-indole-1-ethanamine

Systematic Name

English

1H-Indole-1-ethanamine, 6-chloro-5-fluoro-?-methyl-, (S)-

Systematic Name

English

1H-Indole-1-ethanamine, 6-chloro-5-fluoro-?-methyl-, (?S)-

Systematic Name

English

Code System Code Type Description

PUBCHEM

3045227

Created by admin on Wed Apr 02 15:09:57 GMT 2025 , Edited by admin on Wed Apr 02 15:09:57 GMT 2025

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FDA UNII

A74GH2T4WD

Created by admin on Wed Apr 02 15:09:57 GMT 2025 , Edited by admin on Wed Apr 02 15:09:57 GMT 2025

PRIMARY

CAS

169675-08-5

Created by admin on Wed Apr 02 15:09:57 GMT 2025 , Edited by admin on Wed Apr 02 15:09:57 GMT 2025

PRIMARY

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