SB-408124

CN(C)C1=CC=C(NC(=O)NC2=C3C=C(F)C=C(F)C3=NC(C)=C2)C=C1

InChIKey=JTARFZSNUAGHRB-UHFFFAOYSA-N

InChI=1S/C19H18F2N4O/c1-11-8-17(15-9-12(20)10-16(21)18(15)22-11)24-19(26)23-13-4-6-14(7-5-13)25(2)3/h4-10H,1-3H3,(H2,22,23,24,26)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
Orexin receptor 1 8 Target ID: CHEMBL5113 Sources: https://www.ncbi.nlm.nih.gov/pubmed/14691055	Antagonist 2849		57.0 nM [Ki]

Substance Class	Chemical Created by `admin` on `Wed Apr 02 09:14:44 GMT 2025` Edited by `admin` on `Wed Apr 02 09:14:44 GMT 2025`
Record UNII	C3YT74C744
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

SB408124

Preferred Name

English

SB-408124

Common Name

English

1-(6,8-DIFLUORO-2-METHYL-QUINOLIN-4-YL)-3-(4-DIMETHYLAMINO-PHENYL)-UREA

Systematic Name

English

UREA, N-(6,8-DIFLUORO-2-METHYL-4-QUINOLINYL)-N-(4-(DIMETHYLAMINO)PHENYL)-

Systematic Name

English

N-(6,8-DIFLUORO-2-METHYL-4-QUINOLINYL)-N-(4-(DIMETHYLAMINO)PHENYL)UREA

Systematic Name

English

Code System Code Type Description

FDA UNII

C3YT74C744