U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Wed Apr 02 08:28:57 GMT 2025
Edited
by admin
on Wed Apr 02 08:28:57 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
CGA81G3KR5
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PUCOTENLIMAB
INN  
Official Name English
HX-008
Preferred Name English
pucotenlimab [INN]
Common Name English
Pucotenlimab [WHO-DD]
Common Name English
IMMUNOGLOBULIN G4 (252-THERONINE,306-PROLINE,432-ALANINE), ANTI-(HUMAN PROGRAMMED CELL DEATH 1) (HUMAN-MUS MUSCULUS MONOCLONAL HX008 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL HX008 .KAPPA.-CHAIN, DIMER
Common Name English
HUMANIZED PD-1 BLOCKING ANTIBODY HX-008
Common Name English
HX008
Code English
Code System Code Type Description
CAS
2403647-03-8
Created by admin on Wed Apr 02 08:28:57 GMT 2025 , Edited by admin on Wed Apr 02 08:28:57 GMT 2025
PRIMARY
FDA UNII
CGA81G3KR5
Created by admin on Wed Apr 02 08:28:57 GMT 2025 , Edited by admin on Wed Apr 02 08:28:57 GMT 2025
PRIMARY
INN
11561
Created by admin on Wed Apr 02 08:28:57 GMT 2025 , Edited by admin on Wed Apr 02 08:28:57 GMT 2025
PRIMARY INN
SMS_ID
300000032297
Created by admin on Wed Apr 02 08:28:57 GMT 2025 , Edited by admin on Wed Apr 02 08:28:57 GMT 2025
PRIMARY
NCI_THESAURUS
C160717
Created by admin on Wed Apr 02 08:28:57 GMT 2025 , Edited by admin on Wed Apr 02 08:28:57 GMT 2025
PRIMARY
From To
1_22 1_96
2_22 2_96
2_132 4_218
2_145 2_201
2_259 2_319
1_132 3_218
2_365 2_423
3_23 3_92
3_138 3_198
4_23 4_92
4_138 4_198
1_145 1_201
1_224 2_224
1_227 2_227
1_259 1_319
1_365 1_423
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_295
N 2_295
N 3_85
N 4_85
Related Record Type Details
PROGRAMMED CELL DEATH PROTEIN 1
TARGET -> INHIBITOR
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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