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Details

Stereochemistry RACEMIC
Molecular Formula C11H13NO3.ClH
Molecular Weight 243.687
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MDMC hydrochloride

SMILES

Cl.CNC(C)C(=O)C1=CC2=C(OCO2)C=C1

InChI

InChIKey=GASYWEXOTOXXLK-UHFFFAOYSA-N
InChI=1S/C11H13NO3.ClH/c1-7(12-2)11(13)8-3-4-9-10(5-8)15-6-14-9;/h3-5,7,12H,6H2,1-2H3;1H

HIDE SMILES / InChI

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C11H13NO3
Molecular Weight 207.2258
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Methylone (3, 4-Methylenedioxy-N-methylcathinone), a β-keto analog of 3,4-methylenedioxy-N-methylamphetamine (MDMA) is a stimulant and psychoactive drug. Methylone is a popular drug of abuse that strongly increases the release of the three monoamines: dopamine, serotonin (5-HT) and norepinephrine. In addition, methylone inhibits plasma membrane catecholamine transporters but only weakly inhibit the vesicle transporter. In April 2013, methylone was listed in the Schedule 1 substance under the Controlled Substances Act.

Approval Year

PubMed

PubMed

TitleDatePubMed
Modulation of human GABAA receptor function: a novel mode of action of drugs of abuse.
2011-12
Metabolism of designer drugs of abuse: an updated review.
2010-06-01
Beta-keto amphetamines: studies on the metabolism of the designer drug mephedrone and toxicological detection of mephedrone, butylone, and methylone in urine using gas chromatography-mass spectrometry.
2010-06
Head shop compound abuse amongst attendees of the Drug Treatment Centre Board.
2010-05
Cytotoxic effects of 3,4-methylenedioxy-N-alkylamphetamines, MDMA and its analogues, on isolated rat hepatocytes.
2009-01
[Analysis of designer drugs detected in the products purchased in fiscal year 2006].
2008-10
The disposition into hair of new designer drugs; methylone, MBDB and methcathinone.
2007-08-15
The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain.
2007-03-22
Combined intoxication with methylone and 5-MeO-MIPT.
2007-01-30
Metabolism of the recently encountered designer drug, methylone, in humans and rats.
2006-08
Methylone and mCPP, two new drugs of abuse?
2005-12
Substance Class Chemical
Created
by admin
on Mon Mar 31 20:47:53 GMT 2025
Edited
by admin
on Mon Mar 31 20:47:53 GMT 2025
Record UNII
D930G9LZ75
Record Status Validated (UNII)
Record Version
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Name Type Language
MDMC hydrochloride
Common Name English
3,4-methylenedioxy-N-methylcathinone hydrochloride
Preferred Name English
METHYLONE HYDROCHLORIDE
Common Name English
1-PROPANONE, 1-(1,3-BENZODIOXOL-5-YL)-2-(METHYLAMINO)-, HYDROCHLORIDE (1:1)
Systematic Name English
M1 hydrochloride
Common Name English
1-PROPANONE, 1-(1,3-BENZODIOXOL-5-YL)-2-(METHYLAMINO)-, HYDROCHLORIDE
Systematic Name English
?k-MDMA hydrochloride
Common Name English
M1 (PSYCHEDELIC) hydrochloride
Common Name English
Code System Code Type Description
FDA UNII
D930G9LZ75
Created by admin on Mon Mar 31 20:47:53 GMT 2025 , Edited by admin on Mon Mar 31 20:47:53 GMT 2025
PRIMARY
CAS
186028-80-8
Created by admin on Mon Mar 31 20:47:53 GMT 2025 , Edited by admin on Mon Mar 31 20:47:53 GMT 2025
PRIMARY
PUBCHEM
46738160
Created by admin on Mon Mar 31 20:47:53 GMT 2025 , Edited by admin on Mon Mar 31 20:47:53 GMT 2025
PRIMARY
EPA CompTox
DTXSID40940032
Created by admin on Mon Mar 31 20:47:53 GMT 2025 , Edited by admin on Mon Mar 31 20:47:53 GMT 2025
PRIMARY
DEA NO.
7540
Created by admin on Mon Mar 31 20:47:53 GMT 2025 , Edited by admin on Mon Mar 31 20:47:53 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE