SAPROPTERIN

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C9H15N5O3
Molecular Weight	241.2471
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of SAPROPTERIN

Structure Search

SMILES

[H][C@@]1(CNC2=C(N1)C(=O)N=C(N)N2)[C@@H](O)[C@H](C)O

InChI

InChIKey=FNKQXYHWGSIFBK-RPDRRWSUSA-N

InChI=1S/C9H15N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h3-4,6,12,15-16H,2H2,1H3,(H4,10,11,13,14,17)/t3-,4+,6-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C9H15N5O3
Molecular Weight	241.2471
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 15:49:48 UTC 2023` Edited by `admin` on `Sat Dec 16 15:49:48 UTC 2023`
Record UNII	EGX657432I
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

SAPROPTERIN

Official Name

English

R-THBP

Common Name

English

SAPROPTERIN [MI]

Common Name

English

(6R)-2-AMINO-6-((1R,2S)-1,2-DIHYDROXYPROPYL)-5,6,7,8-TETRAHYDROPTERIDIN-4(1H)-ONE

Systematic Name

English

BH4

Common Name

English

SAPROPTERIN [VANDF]

Common Name

English

6R-BH4

Common Name

English

DAPROPTERIN

Common Name

English

Sapropterin [WHO-DD]

Common Name

English

TETRAHYDROBIOPTERIN

Common Name

English

4(1H)-PTERIDINONE, (6R)-2-AMINO-6-((1R,2S)-1,2-DIHYDROXYPROPYL)-5,6,7,8-TETRAHYDRO-

Systematic Name

English

(6R)-L-ERYTHRO-TETRAHYDROBIOPTERIN

Common Name

English

sapropterin [INN]

Common Name

English

(6R)-2-AMINO-6-((1R,2S)-1,2-DIHYDROXYPROPYL)-5,6,7,8-TETRAHYDRO-4(1H)-PTERIDINONE

Systematic Name

English

Classification Tree Code System Code

LOINC

59247-7

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

LOINC

33877-2

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

WHO-ATC

A16AX07

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

NCI_THESAURUS

C275

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

WHO-VATC

QA16AX07

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

NDF-RT

N0000190483

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

FDA ORPHAN DRUG

181503

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

EU-Orphan Drug

EU/3/05/308

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

NCI_THESAURUS

C1916

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

Code System Code Type Description

CAS

62989-33-7

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

PRIMARY

LACTMED

Sapropterin

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

PRIMARY

ChEMBL

CHEMBL1201774

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

PRIMARY

CHEBI

59560

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

PRIMARY

NDF-RT

N0000190482

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

PRIMARY

Phenylalanine Hydroxylase Activators [MoA]

DRUG BANK

DB00360

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

PRIMARY

SMS_ID

100000084074

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

PRIMARY

CAS

17528-72-2

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

NON-SPECIFIC STEREOCHEMISTRY

IUPHAR

5276

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

PRIMARY

DAILYMED

EGX657432I

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

PRIMARY

INN

6553

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

PRIMARY

WIKIPEDIA

TETRAHYDROBIOPTERIN

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

PRIMARY

NCI_THESAURUS

C78087

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

PRIMARY

RXCUI

753340

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

PRIMARY

RxNorm

NDF-RT

N0000190113

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

PRIMARY

Breast Cancer Resistance Protein Inhibitors [MoA]

EPA CompTox

DTXSID1041138

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

PRIMARY

PUBCHEM

135398654

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

PRIMARY

EVMPD

SUB10445MIG

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

PRIMARY

CAS

27070-47-9

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

ALTERNATIVE

CHEBI

15372

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

PRIMARY

MERCK INDEX

m9775

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

PRIMARY

Merck Index

NDF-RT

N0000185503

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

PRIMARY

P-Glycoprotein Inhibitors [MoA]

DRUG CENTRAL

2612

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

PRIMARY

FDA UNII

EGX657432I

Created by admin on Sat Dec 16 15:49:49 UTC 2023 , Edited by admin on Sat Dec 16 15:49:49 UTC 2023

PRIMARY

Related Record Type Details


					F774380N1W

SAPROPTERIN SESQUIHYDROCHLORIDE

SALT/SOLVATE -> PARENT


					RG277LF5B3

SAPROPTERIN DIHYDROCHLORIDE

SALT/SOLVATE -> PARENT

Related Record Type Details


					EGX657432I

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	ENZYMATIC				ORAL ADMINISTRATION

Tmax	ENZYMATIC				ORAL ADMINISTRATION