?4?2 Nicotinic acetylcholine receptor

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NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 15:22:29 GMT 2025` Edited by `admin` on `Wed Apr 02 15:22:29 GMT 2025`
Protein Type	RECEPTOR
Protein Sub Type	ACETYLCHOLINE RECEPTOR
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	HG7V4AMY2Z
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Neuronal acetylcholine receptor subunit alpha-4/Neuronal acetylcholine receptor subunit beta-2

Preferred Name

English

?4?2 Nicotinic acetylcholine receptor

Common Name

English

?4?2 nAChR

Common Name

English

Code System Code Type Description

FDA UNII

HG7V4AMY2Z

Created by admin on Wed Apr 02 15:22:29 GMT 2025 , Edited by admin on Wed Apr 02 15:22:29 GMT 2025

PRIMARY

UNIPROT

P43681

Created by admin on Wed Apr 02 15:22:29 GMT 2025 , Edited by admin on Wed Apr 02 15:22:29 GMT 2025

PRIMARY

UNIPROT

P17787

Created by admin on Wed Apr 02 15:22:29 GMT 2025 , Edited by admin on Wed Apr 02 15:22:29 GMT 2025

PRIMARY

From	To
5_130	5_144
4_130	4_144
1_133	1_147
3_133	3_147
2_133	2_147
1_197	1_198
3_197	3_198
2_197	2_198

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_29
N	1_79
N	1_146
N	2_29
N	2_79
N	2_146
N	3_29
N	3_79
N	3_146
N	4_26
N	4_143
N	4_460
N	5_26
N	5_143
N	5_460

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Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_243] [2_243] [3_243]				S-PALMITOYL CYSTEINE	08WQ73S7SV

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL