EPIDERMAL GROWTH FACTOR RECEPTOR (EXON 19 DELETION/T790M MUTANT)

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 04:15:16 GMT 2025` Edited by `admin` on `Wed Apr 02 04:15:16 GMT 2025`
Protein Type	RECEPTOR
Protein Sub Type	GROWTH FACTOR RECEPTOR
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	HRV48Z6HOP
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

EGFR EXON19DEL/T790M

Preferred Name

English

EPIDERMAL GROWTH FACTOR RECEPTOR (EXON 19 DELETION/T790M MUTANT)

Common Name

English

HER1 (E746-A750 DELETION/T790M)

Common Name

English

EGFR DEL19/T790M

Common Name

English

EPIDERMAL GROWTH FACTOR RECEPTOR (EXON 19 DELETION, L790M MUTANT)

Common Name

English

EPIDERMAL GROWTH FACTOR RECEPTOR (E746-A750 DELETION/T790M)

Common Name

English

RECEPTOR TYROSINE-PROTEIN KINASE ERBB-1 (E746-A750 DELETION/T790M)

Common Name

English

Code System Code Type Description

UNIPROT

P00533

Created by admin on Wed Apr 02 04:15:16 GMT 2025 , Edited by admin on Wed Apr 02 04:15:16 GMT 2025

PRIMARY

FDA UNII

HRV48Z6HOP

Created by admin on Wed Apr 02 04:15:16 GMT 2025 , Edited by admin on Wed Apr 02 04:15:16 GMT 2025

PRIMARY

From	To
1_7	1_34
1_133	1_163
1_166	1_175
1_170	1_183
1_191	1_199
1_195	1_207
1_208	1_216
1_212	1_224
1_227	1_236
1_240	1_267
1_271	1_283
1_287	1_302
1_305	1_309
1_313	1_338
1_446	1_475
1_482	1_491
1_486	1_499
1_502	1_511
1_515	1_531
1_534	1_547
1_538	1_555
1_558	1_567
1_571	1_593
1_596	1_604
1_600	1_612

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_32
N	1_49
N	1_104
N	1_151
N	1_172
N	1_328
N	1_337
N	1_389
N	1_420
N	1_504
N	1_544
N	1_579
N	1_599

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Structural Modifications

Modification Type	Location Site	Location Type	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_654]	SITE_SPECIFIC	THREONINE PHOSPHATE	3L4WX7B1EI
AMINO ACID SUBSTITUTION	[1_1170]	SITE_SPECIFIC	TILARGININE	27JT06E6GR
AMINO ACID SUBSTITUTION	[1_969] [1_987] [1_1063] [1_1081] [1_1143] [1_1168]		TYROSINE O-PHOSPHATE	2R86C98KDX

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL
Molecular Formula	CHEMICAL