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Details

Stereochemistry ABSOLUTE
Molecular Formula C16H19N3O4S.3H2O
Molecular Weight 403.451
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AMPICILLIN TRIHYDRATE

SMILES

O.O.O.[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](N)C3=CC=CC=C3)C(O)=O

InChI

InChIKey=RXDALBZNGVATNY-CWLIKTDRSA-N
InChI=1S/C16H19N3O4S.3H2O/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;;;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);3*1H2/t9-,10-,11+,14-;;;/m1.../s1

HIDE SMILES / InChI
Molecular Formula C16H19N3O4S
Molecular Weight 349.405
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED
Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
123738
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:02:54 UTC 2023
Edited
by admin
on Fri Dec 15 15:02:54 UTC 2023
Record UNII
HXQ6A1N7R6
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AMPICILLIN TRIHYDRATE
EP   GREEN BOOK   MART.   MI   USP-RS   VANDF   WHO-DD   WHO-IP  
Common Name English
POLY-CILLIN
Common Name English
Ampicillin trihydrate [WHO-DD]
Common Name English
AMPICILLIN/AMPICILLIN TRIHYDRATE [ORANGE BOOK]
Common Name English
AMPICILLIN TRIHYDRATE [VANDF]
Common Name English
AMPICILLIN TRIHYDRATE [MI]
Common Name English
AMPICILLIN TRIHYDRATE [MART.]
Common Name English
AMPICILLIN TRIHYDRATE [EP MONOGRAPH]
Common Name English
AMPICILLIN/AMPICILLIN TRIHYDRATE
ORANGE BOOK  
Common Name English
AMPICILLIN HYDRATE
JAN  
Common Name English
4-THIA-1-AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID, 6-(((2R)-2-AMINO-2-PHENYLACETYL)AMINO)-3,3-DIMETHYL-7-OXO-, HYDRATE (1:3), (2S,5R,6R)-
Systematic Name English
AMINOBENZYLPENICILLIN TRIHYDRATE
Common Name English
AMPICILLIN TRIHYDRATE [USP-RS]
Common Name English
AMPICILLIN TRIHYDRATE [GREEN BOOK]
Common Name English
AMPICILLIN HYDRATE [JAN]
Common Name English
AMPICILLIN TRIHYDRATE [WHO-IP]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C1500
Created by admin on Fri Dec 15 15:02:54 UTC 2023 , Edited by admin on Fri Dec 15 15:02:54 UTC 2023
CFR 21 CFR 522.90A
Created by admin on Fri Dec 15 15:02:54 UTC 2023 , Edited by admin on Fri Dec 15 15:02:54 UTC 2023
CFR 21 CFR 522.90B
Created by admin on Fri Dec 15 15:02:54 UTC 2023 , Edited by admin on Fri Dec 15 15:02:54 UTC 2023
Code System Code Type Description
MERCK INDEX
m1853
Created by admin on Fri Dec 15 15:02:54 UTC 2023 , Edited by admin on Fri Dec 15 15:02:54 UTC 2023
PRIMARY Merck Index
WHO INTERNATIONAL PHARMACOPEIA
AMPICILLIN TRIHYDRATE
Created by admin on Fri Dec 15 15:02:54 UTC 2023 , Edited by admin on Fri Dec 15 15:02:54 UTC 2023
PRIMARY Description: A white or almost white, crystalline powder; odourless or almost odourless. Solubility: Slightly soluble in water; practically insoluble in ethanol (~750 g/l) TS and ether R. Category: Antibiotic. Storage: Ampicillin should be kept in a tightly closed container, protected from light. Labelling: The designation on the container of Ampicillin should state whether the substance is in the anhydrous form or is the trihydrate. Additional information: Even in the absence of light, Ampicillin is gradually degraded on exposure to a humid atmosphere, the decomposition being faster at higher temperatures. Definition: Ampicillin contains not less than 95.0% and not more than 102.0% of C16H19N3O4S, calculated with reference to the anhydrous substance.
RS_ITEM_NUM
1033407
Created by admin on Fri Dec 15 15:02:54 UTC 2023 , Edited by admin on Fri Dec 15 15:02:54 UTC 2023
PRIMARY
CAS
7177-48-2
Created by admin on Fri Dec 15 15:02:54 UTC 2023 , Edited by admin on Fri Dec 15 15:02:54 UTC 2023
PRIMARY
RXCUI
203115
Created by admin on Fri Dec 15 15:02:54 UTC 2023 , Edited by admin on Fri Dec 15 15:02:54 UTC 2023
PRIMARY RxNorm
CHEBI
31209
Created by admin on Fri Dec 15 15:02:54 UTC 2023 , Edited by admin on Fri Dec 15 15:02:54 UTC 2023
PRIMARY
DRUG BANK
DBSALT001206
Created by admin on Fri Dec 15 15:02:54 UTC 2023 , Edited by admin on Fri Dec 15 15:02:54 UTC 2023
PRIMARY
NCI_THESAURUS
C47960
Created by admin on Fri Dec 15 15:02:54 UTC 2023 , Edited by admin on Fri Dec 15 15:02:54 UTC 2023
PRIMARY
ChEMBL
CHEMBL174
Created by admin on Fri Dec 15 15:02:54 UTC 2023 , Edited by admin on Fri Dec 15 15:02:54 UTC 2023
PRIMARY
DAILYMED
HXQ6A1N7R6
Created by admin on Fri Dec 15 15:02:54 UTC 2023 , Edited by admin on Fri Dec 15 15:02:54 UTC 2023
PRIMARY
EVMPD
SUB00509MIG
Created by admin on Fri Dec 15 15:02:54 UTC 2023 , Edited by admin on Fri Dec 15 15:02:54 UTC 2023
PRIMARY
FDA UNII
HXQ6A1N7R6
Created by admin on Fri Dec 15 15:02:54 UTC 2023 , Edited by admin on Fri Dec 15 15:02:54 UTC 2023
PRIMARY
PUBCHEM
23565
Created by admin on Fri Dec 15 15:02:54 UTC 2023 , Edited by admin on Fri Dec 15 15:02:54 UTC 2023
PRIMARY
SMS_ID
100000092549
Created by admin on Fri Dec 15 15:02:54 UTC 2023 , Edited by admin on Fri Dec 15 15:02:54 UTC 2023
PRIMARY
EPA CompTox
DTXSID9020083
Created by admin on Fri Dec 15 15:02:54 UTC 2023 , Edited by admin on Fri Dec 15 15:02:54 UTC 2023
PRIMARY
Related Record Type Details
Structure of AMPICILLIN
ANHYDROUS->SOLVATE
Structure of AMPICILLIN
PARENT -> SALT/SOLVATE
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IMPURITY -> PARENT
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EP
Structure of PENILLOIC ACIDS OF AMPICILLIN
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of (2S,5R,6R)-6-((2,2-DIMETHYLPROPANOYL)AMINO)-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID
IMPURITY -> PARENT
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EP
Structure of AMPICILLINYL-D-PHENYLGLYCINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of DIKETOPIPERAZINES OF AMPICILLIN
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 6-AMINOPENICILLANIC ACID
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of AMPICILLOIC ACID
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of PHENYLGLYCINE, D-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of PHENYLGLYCYLAMPICILLIN, D-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 3,6-DIPHENYLPIPERAZINE-2,5-DIONE, (3R,6R)-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of AMPICILLIN, L-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of AMPICILLIN
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