BERGAMOTTIN

CC(C)=CCC\C(C)=C\COC1=C2C=COC2=CC3=C1C=CC(=O)O3

InChIKey=DBMJZOMNXBSRED-OQLLNIDSSA-N

InChI=1S/C21H22O4/c1-14(2)5-4-6-15(3)9-11-24-21-16-7-8-20(22)25-19(16)13-18-17(21)10-12-23-18/h5,7-10,12-13H,4,6,11H2,1-3H3/b15-9+

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

PubMed

Title	Date	PubMed
Use of comprehensive screening methods to detect selective human CAR activators.	2011-12-15	21924250
In vitro interactions with repeated grapefruit juice administration--to peel or not to peel?	2009-03	19148864
Effects of naturally occurring coumarins on hepatic drug-metabolizing enzymes in mice.	2008-10-15	18692084
Suppressive Effects of Selected Food Phytochemicals on CD74 Expression in NCI-N87 Gastric Carcinoma Cells.	2008-09	18818744
Automated screening with confirmation of mechanism-based inactivation of CYP3A4, CYP2C9, CYP2C19, CYP2D6, and CYP1A2 in pooled human liver microsomes.	2005-08	15860655
The naturally occurring cytochrome P450 (P450) 2B6 K262R mutant of P450 2B6 exhibits alterations in substrate metabolism and inactivation.	2005-06	15769884
Coumarins are competitive inhibitors of cytochrome P450 1B1, with equal potency for allelic variants.	2005-03	15861043
Natural furocoumarins as inducers and inhibitors of cytochrome P450 1A1 in rat hepatocytes.	2005-02-15	15670584
Differential and special properties of the major human UGT1-encoded gastrointestinal UDP-glucuronosyltransferases enhance potential to control chemical uptake.	2004-01-09	14557274
Inhibition of P-glycoprotein transport function by grapefruit juice psoralen.	2001-04	11451028

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:34:04 GMT 2025` Edited by `admin` on `Mon Mar 31 19:34:04 GMT 2025`
Record UNII	JMU611YFRB
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

5-GERANOXYPSORALEN

Preferred Name

English

BERGAMOTTIN

Common Name

English

BERGAMOTTIN [MI]

Common Name

English

BERGAPTIN

Common Name

English

BERGAMOTINE

Common Name

English

7H-FURO(3,2-G)(1)BENZOPYRAN-7-ONE, 4-(((2E)-3,7-DIMETHYL-2,6-OCTADIEN-1-YL)OXY)-

Systematic Name

English

Classification Tree Code System Code

DSLD