U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Wed Apr 02 19:25:49 GMT 2025
Edited
by admin
on Wed Apr 02 19:25:49 GMT 2025
Source Materials Class ORGANISM
Source Materials Type RECOMBINANT VIRUS
Source Materials State LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family Retroviridae
Organism Genus Lentivirus
Organism Species human immunodeficiency virus 1
Infraspecific Type RECOMBINANT VECTOR
Infraspecific Name SIN/LV/MAGE-A4 c1032 TCR/CD8?
Part whole
Record UNII
JT3Q2MC2MT
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Uzatresgene autoleucel vector encoding MAGE-A4 specific T cell receptor (TCR) plus CD8 alpha co-receptor
Preferred Name English
Code System Code Type Description
FDA UNII
JT3Q2MC2MT
Created by admin on Wed Apr 02 19:25:49 GMT 2025 , Edited by admin on Wed Apr 02 19:25:49 GMT 2025
PRIMARY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
GENE_EXPRESSION VECTOR Uzatresgene autoleucel transgene insert encoding MAGE-A4 specific T cell receptor (TCR) plus CD8 alpha co-receptor 3AL52683ZL