Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Wed Apr 02 01:46:33 GMT 2025
by
admin
on
Wed Apr 02 01:46:33 GMT 2025
|
| Protein Sub Type | |
| Sequence Type | COMPLETE |
| Record UNII |
LD9PUL4TEM
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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LD9PUL4TEM
Created by
admin on Wed Apr 02 01:46:33 GMT 2025 , Edited by admin on Wed Apr 02 01:46:33 GMT 2025
|
PRIMARY | |||
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P31751
Created by
admin on Wed Apr 02 01:46:33 GMT 2025 , Edited by admin on Wed Apr 02 01:46:33 GMT 2025
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PRIMARY | |||
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AKT2
Created by
admin on Wed Apr 02 01:46:33 GMT 2025 , Edited by admin on Wed Apr 02 01:46:33 GMT 2025
|
PRIMARY | |||
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P31751
Created by
admin on Wed Apr 02 01:46:33 GMT 2025 , Edited by admin on Wed Apr 02 01:46:33 GMT 2025
|
PRIMARY |
| From | To |
|---|---|
| 1_60 | 1_77 |
| 1_297 | 1_311 |
| Glycosylation Type | HUMAN |
| Glycosylation Link Type | Site |
|---|---|
| O | 1_128 |
| O | 1_131 |
| O | 1_306 |
| O | 1_313 |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
ALLOSTERIC
IC50
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INHIBITOR -> TARGET |
ATP competitive
ASSAY (Functional)
IC50
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INHIBITOR -> TARGET |
ALLOSTERIC INHIBITOR
IC50
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
ALLOSTERIC
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INHIBITOR -> TARGET |
Notably, the antitumor effect of miR-193a-3p transfection in glioma cells may be due to the miR-193a-3p–induced inhibition of AKT2 expression caused by the suppression of ALKBH5 expression.
PRECLINICAL
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INHIBITOR -> TARGET |
AT 10mM ATP and 36 nM at 2 mM ATP)
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ACTIVATOR -> TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
Inhibits phosphorylation of AKT presumably prevents IP3 binding.
IC50
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| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT | CHEMICAL |
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| Molecular Formula | CHEMICAL |
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