Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Wed Apr 02 01:47:17 GMT 2025
by
admin
on
Wed Apr 02 01:47:17 GMT 2025
|
| Protein Sub Type | |
| Sequence Origin | HUMAN |
| Sequence Type | COMPLETE |
| Record UNII |
P93F057EMS
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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Q16236
Created by
admin on Wed Apr 02 01:47:17 GMT 2025 , Edited by admin on Wed Apr 02 01:47:17 GMT 2025
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PRIMARY | |||
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P93F057EMS
Created by
admin on Wed Apr 02 01:47:17 GMT 2025 , Edited by admin on Wed Apr 02 01:47:17 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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INDUCER -> TARGET |
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ACTIVATOR -> TARGET |
Bardoxolone methyl covalently binds to the reactive cysteine residue(s) of Keap1, releasing Nrf2 from the proteasome pathway into the nucleus.
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ACTIVATOR -> TARGET |
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ACTIVATOR -> TARGET |
Reacts with reactive cysteine residues through covalent, resulting in the conformational changes of Keap1 and the release of Nrf2 from Keap1.
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ACTIVATOR -> TARGET |
Baicalein exerts its effects by inactivating Keap1 through interaction with the cysteine thiol residues of Keap1, subsequently inducing Nrf2 nuclear translocation.
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ACTIVATOR -> TARGET |
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ACTIVATOR -> TARGET |
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INHIBITOR -> TARGET |
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ACTIVATOR -> TARGET |
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ACTIVATOR -> TARGET |
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| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| Molecular Formula | CHEMICAL |
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| MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
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