Cesnicabtagene autoleucel lentiviral vector

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NCATS

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Wed Apr 02 19:47:06 GMT 2025` Edited by `admin` on `Wed Apr 02 19:47:06 GMT 2025`
Source Materials Class	ORGANISM
Source Materials Type	RECOMBINANT VIRUS
Source Materials State	LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family	Retroviridae
Organism Genus	Lentivirus
Organism Species	human immunodeficiency virus 1
Infraspecific Type	RECOMBINANT VECTOR
Infraspecific Name	SIN/LV/EF-1?-anti-BCMA CAR
Part	whole
Record UNII	PKW5458C47
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Cesnicabtagene autoleucel lentiviral vector

Preferred Name

English

Code System Code Type Description

FDA UNII

PKW5458C47

Created by admin on Wed Apr 02 19:47:06 GMT 2025 , Edited by admin on Wed Apr 02 19:47:06 GMT 2025

PRIMARY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
INSERTED GENE EXPRESSION VECTOR					Cesnicabtagene autoleucel transgene insert encoding anti-BCMA chimeric antigen receptor (CAR)	5R4T3733Y7