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Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Tue Apr 01 16:52:10 GMT 2025
Edited
by admin
on Tue Apr 01 16:52:10 GMT 2025
Protein Sub Type
Sequence Type COMPLETE
Record UNII
QJ2A67X342
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PAF-R
Preferred Name English
PLATELET-ACTIVATING FACTOR RECEPTOR
Common Name English
PLATELET-ACTIVATING FACTOR RECEPTOR (HUMAN CLONE MGC:17210 IMAGE:4343214)
Common Name English
PAFR
Common Name English
PTAFR
Common Name English
Code System Code Type Description
PHAROS
P25105
Created by admin on Tue Apr 01 16:52:10 GMT 2025 , Edited by admin on Tue Apr 01 16:52:10 GMT 2025
PRIMARY
CAS
551895-30-8
Created by admin on Tue Apr 01 16:52:10 GMT 2025 , Edited by admin on Tue Apr 01 16:52:10 GMT 2025
ALTERNATIVE
CAS
624643-14-7
Created by admin on Tue Apr 01 16:52:10 GMT 2025 , Edited by admin on Tue Apr 01 16:52:10 GMT 2025
ALTERNATIVE
WIKIPEDIA
PLATELET-ACTIVATING FACTOR RECEPTOR
Created by admin on Tue Apr 01 16:52:10 GMT 2025 , Edited by admin on Tue Apr 01 16:52:10 GMT 2025
PRIMARY
CAS
459522-58-8
Created by admin on Tue Apr 01 16:52:10 GMT 2025 , Edited by admin on Tue Apr 01 16:52:10 GMT 2025
ALTERNATIVE
CAS
481306-66-5
Created by admin on Tue Apr 01 16:52:10 GMT 2025 , Edited by admin on Tue Apr 01 16:52:10 GMT 2025
ALTERNATIVE
CAS
480084-59-1
Created by admin on Tue Apr 01 16:52:10 GMT 2025 , Edited by admin on Tue Apr 01 16:52:10 GMT 2025
PRIMARY
CAS
481200-26-4
Created by admin on Tue Apr 01 16:52:10 GMT 2025 , Edited by admin on Tue Apr 01 16:52:10 GMT 2025
ALTERNATIVE
UNIPROT
P25105
Created by admin on Tue Apr 01 16:52:10 GMT 2025 , Edited by admin on Tue Apr 01 16:52:10 GMT 2025
PRIMARY
FDA UNII
QJ2A67X342
Created by admin on Tue Apr 01 16:52:10 GMT 2025 , Edited by admin on Tue Apr 01 16:52:10 GMT 2025
PRIMARY
CAS
481306-67-6
Created by admin on Tue Apr 01 16:52:10 GMT 2025 , Edited by admin on Tue Apr 01 16:52:10 GMT 2025
ALTERNATIVE
CAS
623884-54-8
Created by admin on Tue Apr 01 16:52:10 GMT 2025 , Edited by admin on Tue Apr 01 16:52:10 GMT 2025
ALTERNATIVE
From To
1_90 1_173
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_169
Related Record Type Details
Structure of MODIPAFANT
INHIBITOR -> TARGET
Structure of NUPAFANT
INHIBITOR -> TARGET
Structure of BEPAFANT
INHIBITOR -> TARGET
Structure of PLATELET-ACTIVATING FACTOR
AGONIST -> TARGET
Human PAF receptor was expressed in CHO cells. Measured displacement of [3H]WEB 2086 by PAF.
BINDING
IC50
Structure of ISRAPAFANT
INHIBITOR -> TARGET
Structure of APAFANT
INHIBITOR -> TARGET
Binding Assay
IC50
Structure of PLATELET-ACTIVATING FACTOR
AGONIST -> TARGET
Structure of NERATINIB
INHIBITOR->OFF-TARGET
Structure of SETIPAFANT
INHIBITOR -> TARGET
Structure of ROCEPAFANT
INHIBITOR -> TARGET
Structure of TULOPAFANT
INHIBITOR -> TARGET
Structure of LEXIPAFANT
INHIBITOR -> TARGET
Structure of NERATINIB
INHIBITOR -> TARGET
Structure of DACOPAFANT
INHIBITOR -> TARGET
Structure of Minopafant ion
INHIBITOR -> TARGET
Structure of FOROPAFANT
INHIBITOR -> TARGET
Structure of [3H] C18-PAF
LIGAND->TARGET
Binding assay
Kd
Structure of [(6R,8S)-6-(2-Chlorophenyl)-6,7,8,9-tetrahydro-1-methyl-4H,5H-cyclopenta[4,5]thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-8-yl][(2S,6S)-2,6-dimethyl-4-morpholinyl]methanone
INHIBITOR -> TARGET
IN-VITRO
ED50
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT CHEMICAL
NIH
NCATS
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