TYROSINE-PROTEIN KINASE BTK

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 18:41:27 GMT 2025` Edited by `admin` on `Tue Apr 01 18:41:27 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	SBH6S6T2J2
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TYROSINE-PROTEIN KINASE BTK

Common Name

English

AGAMMAGLOBULINEMIA TYROSINE KINASE

Preferred Name

English

BRUTON TYROSINE KINASE

Common Name

English

BPK

Common Name

English

AGMX1

Common Name

English

BRUTON'S TYROSINE KINASE

Common Name

English

B-CELL PROGENITOR KINASE

Common Name

English

ATK

Common Name

English

Classification Tree Code System Code

EU-Orphan Drug

EU/3/17/1951

Created by admin on Tue Apr 01 18:41:27 GMT 2025 , Edited by admin on Tue Apr 01 18:41:27 GMT 2025

Code System Code Type Description

UNIPROT

Q06187

Created by admin on Tue Apr 01 18:41:27 GMT 2025 , Edited by admin on Tue Apr 01 18:41:27 GMT 2025

PRIMARY

PHAROS

Q06187

Created by admin on Tue Apr 01 18:41:27 GMT 2025 , Edited by admin on Tue Apr 01 18:41:27 GMT 2025

PRIMARY

FDA UNII

SBH6S6T2J2

Created by admin on Tue Apr 01 18:41:27 GMT 2025 , Edited by admin on Tue Apr 01 18:41:27 GMT 2025

PRIMARY

Linkage Type	Residue Index
COORDINATION COMPOUND	1_142	1_153	1_154	1_164

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Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_142] [1_153] [1_154] [1_164]	SITE_SPECIFIC			C3H1-TYPE ZINC FINGER	JKX41V9FYM
AMINO ACID SUBSTITUTION	[1_20] [1_54] [1_114] [1_622] [1_658]				DEXFOSFOSERINE	VI4F0K069V

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL