PREDNISONE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C21H26O5
Molecular Weight	358.4281
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PREDNISONE

Structure Search

SMILES

[H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)CC(=O)[C@@]3([H])[C@@]2([H])CCC4=CC(=O)C=C[C@]34C

InChI

InChIKey=XOFYZVNMUHMLCC-ZPOLXVRWSA-N

InChI=1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C21H26O5
Molecular Weight	358.4281
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	6 / 6
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:51:36 UTC 2023` Edited by `admin` on `Fri Dec 15 15:51:36 UTC 2023`
Record UNII	VB0R961HZT
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

PREDNISONE

Official Name

English

17,21-Dihydroxypregna-1,4-diene-3,11,20-trione

Systematic Name

English

PREGNA-1,4-DIENE-3,11,20-TRIONE, 17,21-DIHYDROXY-

Systematic Name

English

PREDNISONE TABLETS [USP-RS]

Common Name

English

PREDNISONE INTENSOL

Brand Name

English

Prednisone [WHO-DD]

Common Name

English

SUPERCORTIL

Common Name

English

METACORTANDRACIN

Common Name

English

PREDNISONE [USP MONOGRAPH]

Common Name

English

PREDNISONE ANHYDROUS

Common Name

English

3EN3HG4WSW

Common Name

English

PREDNISONE [GREEN BOOK]

Common Name

English

NSC-10023

Code

English

prednisone [INN]

Common Name

English

DELTASONE

Brand Name

English

DEHYDROCORTISONE

Common Name

English

PREDNISONE [USP-RS]

Common Name

English

PREDNISONE [ORANGE BOOK]

Common Name

English

PREDNISONE [EP MONOGRAPH]

Common Name

English

PREDNISONE TABLETS

Common Name

English

PREDNISONE [IARC]

Common Name

English

PREDNISONE [VANDF]

Common Name

English

PREDNISONE [HSDB]

Common Name

English

PREDNISONE [MART.]

Common Name

English

PREDNISONE [MI]

Common Name

English

DECORTIN

Brand Name

English

PREDNISOLONE IMPURITY B [EP IMPURITY]

Common Name

English

Classification Tree Code System Code

WHO-ATC

H02AB07

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

WHO-ATC

A07EA03

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

WHO-VATC

QH02AB07

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

NCI_THESAURUS

C521

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

IARC

Prednisone

WHO-VATC

QH02AB57

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

CFR

21 CFR 522.1890

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

LIVERTOX

795

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

NDF-RT

N0000175450

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

WHO-VATC

QA07EA03

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

NDF-RT

N0000175576

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

Code System Code Type Description

NCI_THESAURUS

C770

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

PRIMARY

RXCUI

8640

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

PRIMARY

RxNorm

HSDB

3168

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

PRIMARY

MERCK INDEX

m9112

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

PRIMARY

Merck Index

RS_ITEM_NUM

1559006

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

PRIMARY

FDA UNII

VB0R961HZT

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

PRIMARY

CHEBI

8382

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

PRIMARY

INN

536

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

PRIMARY

DRUG BANK

DB00635

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

PRIMARY

DRUG CENTRAL

2253

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

PRIMARY

ECHA (EC/EINECS)

200-160-3

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

PRIMARY

IUPHAR

7096

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

PRIMARY

EVMPD

SUB10020MIG

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

PRIMARY

DAILYMED

VB0R961HZT

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

PRIMARY

RS_ITEM_NUM

1559505

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

ALTERNATIVE

SMS_ID

100000091943

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

PRIMARY

PUBCHEM

5865

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

PRIMARY

MESH

D011241

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

PRIMARY

EPA CompTox

DTXSID4021185

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

PRIMARY

LACTMED

Prednisone

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

PRIMARY

ChEMBL

CHEMBL635

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

PRIMARY

NSC

10023

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

PRIMARY

CAS

53-03-2

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

PRIMARY

WIKIPEDIA

PREDNISONE

Created by admin on Fri Dec 15 15:51:36 UTC 2023 , Edited by admin on Fri Dec 15 15:51:36 UTC 2023

PRIMARY

Related Record Type Details


					KN24QP9M3Q

11.BETA.-HYDROXYSTEROID DEHYDROGENASE TYPE 1

METABOLIC ENZYME -> SUBSTRATE

Related Record Type Details


					V27W9254FZ

CORTISONE

METABOLITE -> PARENT

Interaction Type:

MINOR

Qualification:

URINE

Amount:


					Z40D3IQ900

HYDROXYCORTISONE, 6.BETA.-

METABOLITE -> PARENT

Interaction Type:

MINOR

Qualification:

URINE

Amount:


					60415ASG86

20-HYDROXYPREDNISOLONE, (20R)-

METABOLITE -> PARENT

Interaction Type:

MINOR

Qualification:

URINE

Amount:


					9PHQ9Y1OLM

METABOLITE ACTIVE -> PRODRUG

Amount:


					1S41ND2459

20-HYDROXYPREDNISOLONE, (20S)-

METABOLITE -> PARENT

Interaction Type:

MINOR

Qualification:

URINE

Amount:

Related Record Type Details


					OU93QEL83U

PREDNISONE ACETATE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					WGZ946T9TP

(17.ALPHA.)-17-HYDROXY-3,11-DIOXOANDROSTA-1,4-DIENE-17-CARBOXYLIC ACID

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

8B2807733D

PREDNISOLONE ACETATE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					9PHQ9Y1OLM

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					ZCF6ZW8234

17,21-DIHYDROXYPREGNA-1,4,9(11)-TRIENE-3,20-DIONE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					P98T8D7BVX

PREDNISONE-21-ALDEHYDE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					VR7WQ2G5Z1

1-DEHYDROADRENOSTERONE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					V27W9254FZ

CORTISONE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					9PHQ9Y1OLM

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC

MAXIMUM TOLERATED DOSE	TOXICITY

Volume of Distribution	PHARMACOKINETIC

Tmax	PHARMACOKINETIC				PREDNISOLONE (ACTIVE METABOLITE), ORAL PHARMACOKINETIC DELAYED-RELEASE, ORAL PHARMACOKINETIC

ORAL BIOAVAILABILITY	PHARMACOKINETIC