U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Wed Apr 02 20:59:41 GMT 2025
Edited
by admin
on Wed Apr 02 20:59:41 GMT 2025
Source Materials Class ORGANISM
Source Materials Type RECOMBINANT VIRUS
Source Materials State Self-inactivating, non-replicating
Organism Family Retroviridae
Organism Genus Lentivirus
Organism Species human immunodeficiency virus 1
Infraspecific Type RECOMBINANT VECTOR
Infraspecific Name Talicabtagene autoleucel LV (HCAR19)
Part whole
Record UNII
XYJ4596Q2U
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Talicabtagene autoleucel lentiviral vector
Common Name English
Talicabtagene autoleucel lentiviral vector encoding a chimeric antigen receptor (CAR) targeting CD19
Preferred Name English
Code System Code Type Description
FDA UNII
XYJ4596Q2U
Created by admin on Wed Apr 02 20:59:41 GMT 2025 , Edited by admin on Wed Apr 02 20:59:41 GMT 2025
PRIMARY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
INSERTED GENE EXPRESSION VECTOR Talicabtagene autoleucel transgene insert W27MEN4E3D