OXARBAZOLE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C21H19NO4
Molecular Weight	349.3799
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of OXARBAZOLE

Structure Search

SMILES

COC1=CC2=C(C=C1)N(C(=O)C3=CC=CC=C3)C4=C2CC(CC4)C(O)=O

InChI

InChIKey=ZNHCPKKNDKCPDG-UHFFFAOYSA-N

InChI=1S/C21H19NO4/c1-26-15-8-10-19-17(12-15)16-11-14(21(24)25)7-9-18(16)22(19)20(23)13-5-3-2-4-6-13/h2-6,8,10,12,14H,7,9,11H2,1H3,(H,24,25)

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/115021

Oxarbazole was developed as an antiasthmatic agent that inhibited the only bronchoconstriction induced by immune complexes. This drug has never been marketed.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Absorption and disposition of oxarbazole in man and laboratory animals.	1978-01-01	23278
Evaluation of the antiasthmatic potential of oxarbazole in guinea pigs.	1978	733892

Patents

Patents

Name

Type

Language

OXARBAZOLE

Official Name

English

WIN 34284

Preferred Name

English

9-Benzoyl-1,2,3,4-tetrahydro-6-methoxycarbazole-3-carboxylic acid

Systematic Name

English

WIN-34284

Code

English

oxarbazole [INN]

Common Name

English

OXARBAZOLE [USAN]

Common Name

English

1H-CARBAZOLE-3-CARBOXYLIC ACID, 9-BENZOYL-2,3,4,9-TETRAHYDRO-6-METHOXY-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29712

Created by admin on Wed Apr 02 07:50:09 GMT 2025 , Edited by admin on Wed Apr 02 07:50:09 GMT 2025

Code System Code Type Description

CAS

35578-20-2

Created by admin on Wed Apr 02 07:50:09 GMT 2025 , Edited by admin on Wed Apr 02 07:50:09 GMT 2025

PRIMARY

ChEMBL

CHEMBL2105332

Created by admin on Wed Apr 02 07:50:09 GMT 2025 , Edited by admin on Wed Apr 02 07:50:09 GMT 2025

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NCI_THESAURUS

C81436

Created by admin on Wed Apr 02 07:50:09 GMT 2025 , Edited by admin on Wed Apr 02 07:50:09 GMT 2025

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EVMPD

SUB09503MIG

Created by admin on Wed Apr 02 07:50:09 GMT 2025 , Edited by admin on Wed Apr 02 07:50:09 GMT 2025

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SMS_ID

100000083032

Created by admin on Wed Apr 02 07:50:09 GMT 2025 , Edited by admin on Wed Apr 02 07:50:09 GMT 2025

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PUBCHEM

37184

Created by admin on Wed Apr 02 07:50:09 GMT 2025 , Edited by admin on Wed Apr 02 07:50:09 GMT 2025

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MESH

C016025

Created by admin on Wed Apr 02 07:50:09 GMT 2025 , Edited by admin on Wed Apr 02 07:50:09 GMT 2025

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EPA CompTox

DTXSID00865777

Created by admin on Wed Apr 02 07:50:09 GMT 2025 , Edited by admin on Wed Apr 02 07:50:09 GMT 2025

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FDA UNII

A34YCH7N8A

Created by admin on Wed Apr 02 07:50:09 GMT 2025 , Edited by admin on Wed Apr 02 07:50:09 GMT 2025

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INN

4289

Created by admin on Wed Apr 02 07:50:09 GMT 2025 , Edited by admin on Wed Apr 02 07:50:09 GMT 2025

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ACTIVE MOIETY


					A34YCH7N8A

METABOLITE (PARENT)


					7C0QD228MK

1H-CARBAZOLE-3-CARBOXYLIC ACID, 9-BENZOYL-2,3,4,9-TETRAHYDRO-6-HYDROXY-