OXARBAZOLE

Details

Stereochemistry	RACEMIC
Molecular Formula	C21H19NO4
Molecular Weight	349.3799
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC2=C(C=C1)N(C(=O)C3=CC=CC=C3)C4=C2CC(CC4)C(O)=O

InChI

InChIKey=ZNHCPKKNDKCPDG-UHFFFAOYSA-N

InChI=1S/C21H19NO4/c1-26-15-8-10-19-17(12-15)16-11-14(21(24)25)7-9-18(16)22(19)20(23)13-5-3-2-4-6-13/h2-6,8,10,12,14H,7,9,11H2,1H3,(H,24,25)

HIDE SMILES / InChI

Molecular Formula	C21H19NO4
Molecular Weight	349.3799
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/115021

Oxarbazole was developed as an antiasthmatic agent that inhibited the only bronchoconstriction induced by immune complexes. This drug has never been marketed.

Approval Year

PubMed

Title	Date	PubMed
Absorption and disposition of oxarbazole in man and laboratory animals.	1978-01-01	23278
Evaluation of the antiasthmatic potential of oxarbazole in guinea pigs.	1978	733892

Patents

Substance Class	Chemical Created by `admin` on `Wed Apr 02 07:50:09 GMT 2025` Edited by `admin` on `Wed Apr 02 07:50:09 GMT 2025`
Record UNII	A34YCH7N8A
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

OXARBAZOLE

Official Name

English

WIN 34284

Preferred Name

English

9-Benzoyl-1,2,3,4-tetrahydro-6-methoxycarbazole-3-carboxylic acid

Systematic Name

English

WIN-34284

Code

English

oxarbazole [INN]

Common Name

English

OXARBAZOLE [USAN]

Common Name

English

1H-CARBAZOLE-3-CARBOXYLIC ACID, 9-BENZOYL-2,3,4,9-TETRAHYDRO-6-METHOXY-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29712