U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Mon Mar 31 20:49:33 GMT 2025
Edited
by admin
on Mon Mar 31 20:49:33 GMT 2025
Protein Type MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type IGG2
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
1568H6A58U
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CDX-011
Preferred Name English
GLEMBATUMUMAB VEDOTIN
INN   USAN   WHO-DD  
INN   USAN  
Official Name English
GLEMBATUMUMAB VEDOTIN [USAN]
Common Name English
CR011-VCMMAE
Code English
Glembatumumab vedotin [WHO-DD]
Common Name English
CR-011-VCMMAE
Code English
glembatumumab vedotin [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C575
Created by admin on Mon Mar 31 20:49:33 GMT 2025 , Edited by admin on Mon Mar 31 20:49:33 GMT 2025
NCI_THESAURUS C129823
Created by admin on Mon Mar 31 20:49:33 GMT 2025 , Edited by admin on Mon Mar 31 20:49:33 GMT 2025
Code System Code Type Description
MESH
C551271
Created by admin on Mon Mar 31 20:49:33 GMT 2025 , Edited by admin on Mon Mar 31 20:49:33 GMT 2025
PRIMARY
FDA UNII
1568H6A58U
Created by admin on Mon Mar 31 20:49:33 GMT 2025 , Edited by admin on Mon Mar 31 20:49:33 GMT 2025
PRIMARY
MESH
C541991
Created by admin on Mon Mar 31 20:49:33 GMT 2025 , Edited by admin on Mon Mar 31 20:49:33 GMT 2025
PRIMARY
SMS_ID
100000166721
Created by admin on Mon Mar 31 20:49:33 GMT 2025 , Edited by admin on Mon Mar 31 20:49:33 GMT 2025
PRIMARY
CAS
1182215-65-1
Created by admin on Mon Mar 31 20:49:33 GMT 2025 , Edited by admin on Mon Mar 31 20:49:33 GMT 2025
PRIMARY
ChEMBL
CHEMBL1743028
Created by admin on Mon Mar 31 20:49:33 GMT 2025 , Edited by admin on Mon Mar 31 20:49:33 GMT 2025
PRIMARY
NCI_THESAURUS
C78449
Created by admin on Mon Mar 31 20:49:33 GMT 2025 , Edited by admin on Mon Mar 31 20:49:33 GMT 2025
PRIMARY
WIKIPEDIA
GLEMBATUMUMAB VEDOTIN
Created by admin on Mon Mar 31 20:49:33 GMT 2025 , Edited by admin on Mon Mar 31 20:49:33 GMT 2025
PRIMARY
INN
10123
Created by admin on Mon Mar 31 20:49:33 GMT 2025 , Edited by admin on Mon Mar 31 20:49:33 GMT 2025
PRIMARY
EVMPD
SUB180927
Created by admin on Mon Mar 31 20:49:33 GMT 2025 , Edited by admin on Mon Mar 31 20:49:33 GMT 2025
PRIMARY
DRUG BANK
DB05996
Created by admin on Mon Mar 31 20:49:33 GMT 2025 , Edited by admin on Mon Mar 31 20:49:33 GMT 2025
PRIMARY
USAN
XX-40
Created by admin on Mon Mar 31 20:49:33 GMT 2025 , Edited by admin on Mon Mar 31 20:49:33 GMT 2025
PRIMARY
From To
1_22 1_97
1_146 1_202
1_259 1_319
1_365 2_423
2_22 2_97
2_146 2_202
2_259 2_319
1_365 2_423
3_23 3_88
3_135 3_195
4_23 4_88
4_135 4_195
1_133 3_215
2_133 4_215
1_221 2_221
1_222 2_222
1_225 2_225
1_228 2_228
Glycosylation Link Type Site
N 1_295
N 2_295
Related Record Type Details
Structure of VEDOTIN FRAGMENT
CONJUGATE COMPONENT->CONJUGATE
TRANSMEMBRANE GLYCOPROTEIN NMB
TARGET -> INHIBITOR
Related Record Type Details
GLEMBATUMUMAB VEDOTIN
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
SUBSTITUTION [1_133] [1_221] [1_222] [1_225] [1_228] [2_133] [2_221] [2_222] [2_225] [2_228] [3_215] [4_215] C Amount: Cysteinyl vedotin 6603L01WUR
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:FORMULA CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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