VABORBACTAM

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C12H16BNO5S
Molecular Weight	297.135
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of VABORBACTAM

Structure Search

SMILES

OB1O[C@H](CC(O)=O)CC[C@@H]1NC(=O)CC2=CC=CS2

InChI

InChIKey=IOOWNWLVCOUUEX-WPRPVWTQSA-N

InChI=1S/C12H16BNO5S/c15-11(7-9-2-1-5-20-9)14-10-4-3-8(6-12(16)17)19-13(10)18/h1-2,5,8,10,18H,3-4,6-7H2,(H,14,15)(H,16,17)/t8-,10-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C12H16BNO5S
Molecular Weight	297.135
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:06:50 UTC 2023` Edited by `admin` on `Sat Dec 16 08:06:50 UTC 2023`
Record UNII	1C75676F8V
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

VABORBACTAM

Official Name

English

VABORBACTAM [USAN]

Common Name

English

RPX-7009

Code

English

VABORBACTAM [ORANGE BOOK]

Common Name

English

1,2-OXABORINANE-6-ACETIC ACID, 2-HYDROXY-3-((2-(2-THIENYL)ACETYL)AMINO)-, (3R,6S)-

Systematic Name

English

Vaborbactam [WHO-DD]

Common Name

English

RPX7009

Code

English

CARBAVANCE COMPONENT VABORBACTAM

Brand Name

English

VABORBACTAM COMPONENT OF CARBAVANCE

Brand Name

English

VABOMERE COMPONENT VABORBACTAM

Brand Name

English

vaborbactam [INN]

Common Name

English

VABORBACTAM [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C471

Created by admin on Sat Dec 16 08:06:50 UTC 2023 , Edited by admin on Sat Dec 16 08:06:50 UTC 2023

WHO-ATC

J01DH52

Created by admin on Sat Dec 16 08:06:50 UTC 2023 , Edited by admin on Sat Dec 16 08:06:50 UTC 2023

NDF-RT

N0000175930

Created by admin on Sat Dec 16 08:06:50 UTC 2023 , Edited by admin on Sat Dec 16 08:06:50 UTC 2023

Code System Code Type Description

WIKIPEDIA

Vaborbactam

Created by admin on Sat Dec 16 08:06:50 UTC 2023 , Edited by admin on Sat Dec 16 08:06:50 UTC 2023

PRIMARY

DRUG CENTRAL

5253

Created by admin on Sat Dec 16 08:06:50 UTC 2023 , Edited by admin on Sat Dec 16 08:06:50 UTC 2023

PRIMARY

INN

10182

Created by admin on Sat Dec 16 08:06:50 UTC 2023 , Edited by admin on Sat Dec 16 08:06:50 UTC 2023

PRIMARY

SMS_ID

100000171856

Created by admin on Sat Dec 16 08:06:50 UTC 2023 , Edited by admin on Sat Dec 16 08:06:50 UTC 2023

PRIMARY

DRUG BANK

DB12107

Created by admin on Sat Dec 16 08:06:50 UTC 2023 , Edited by admin on Sat Dec 16 08:06:50 UTC 2023

PRIMARY

USAN

DE-105

Created by admin on Sat Dec 16 08:06:50 UTC 2023 , Edited by admin on Sat Dec 16 08:06:50 UTC 2023

PRIMARY

NCI_THESAURUS

C152810

Created by admin on Sat Dec 16 08:06:50 UTC 2023 , Edited by admin on Sat Dec 16 08:06:50 UTC 2023

PRIMARY

FDA UNII

1C75676F8V

Created by admin on Sat Dec 16 08:06:50 UTC 2023 , Edited by admin on Sat Dec 16 08:06:50 UTC 2023

PRIMARY

CAS

1575712-03-6

Created by admin on Sat Dec 16 08:06:50 UTC 2023 , Edited by admin on Sat Dec 16 08:06:50 UTC 2023

NO STRUCTURE GIVEN

DAILYMED

1C75676F8V

Created by admin on Sat Dec 16 08:06:50 UTC 2023 , Edited by admin on Sat Dec 16 08:06:50 UTC 2023

PRIMARY

MERCK INDEX

m12030

Created by admin on Sat Dec 16 08:06:50 UTC 2023 , Edited by admin on Sat Dec 16 08:06:50 UTC 2023

PRIMARY

RXCUI

1945213

Created by admin on Sat Dec 16 08:06:50 UTC 2023 , Edited by admin on Sat Dec 16 08:06:50 UTC 2023

PRIMARY

EPA CompTox

DTXSID901027690

Created by admin on Sat Dec 16 08:06:50 UTC 2023 , Edited by admin on Sat Dec 16 08:06:50 UTC 2023

PRIMARY

PUBCHEM

56649692

Created by admin on Sat Dec 16 08:06:50 UTC 2023 , Edited by admin on Sat Dec 16 08:06:50 UTC 2023

PRIMARY

CAS

1360457-46-0

Created by admin on Sat Dec 16 08:06:50 UTC 2023 , Edited by admin on Sat Dec 16 08:06:50 UTC 2023

PRIMARY

Related Record Type Details


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					1C75676F8V

EXCRETED UNCHANGED

Interaction Type:

AMOUNT EXCRETED

Qualification:

URINE

Amount:


					0JMN4Q4EUY

CARBAPENEM-HYDROLYZING BETA-LACTAMASE KPC

TARGET -> INHIBITOR

Comments:

KOFF=0.000017 (1/S), RESIDENCE TIME=992 (MIN), STOICHIOMETRY=1

Interaction Type:

REVERSIBLE

Qualification:

Kd

Amount:

Related Record Type Details


					1C75676F8V

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC