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Details

Stereochemistry ACHIRAL
Molecular Formula C28H29F2N3O
Molecular Weight 461.5462
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PIMOZIDE

SMILES

FC1=CC=C(C=C1)C(CCCN2CCC(CC2)N3C(=O)NC4=CC=CC=C34)C5=CC=C(F)C=C5

InChI

InChIKey=YVUQSNJEYSNKRX-UHFFFAOYSA-N
InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34)

HIDE SMILES / InChI
Molecular Formula C28H29F2N3O
Molecular Weight 461.5462
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 17:29:47 UTC 2023
Edited
by admin
on Sat Dec 16 17:29:47 UTC 2023
Record UNII
1HIZ4DL86F
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PIMOZIDE
EP   INN   JAN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD  
INN   USAN  
Official Name English
ORAP
Brand Name English
PIMOZIDE [USP MONOGRAPH]
Common Name English
PIMOZIDE [ORANGE BOOK]
Common Name English
MCN-JR-6238
Code English
Pimozide [WHO-DD]
Common Name English
2H-BENZIMIDAZOL-2-ONE, 1-(1-(4,4-BIS(4-FLUOROPHENYL)BUTYL)-4-PIPERIDINYL)-1,3-DIHYDRO
Common Name English
PIMOZIDE [USAN]
Common Name English
NSC-170984
Code English
PIMOZIDE [MART.]
Common Name English
PIMOZIDE [JAN]
Common Name English
PIMOZIDE [EP MONOGRAPH]
Common Name English
pimozide [INN]
Common Name English
1-[1-[4,4-Bis(4-fluorophenyl)butyl]-4-piperidyl]-2-benzimidazolinone
Systematic Name English
R 623
Code English
PIMOZIDE [MI]
Common Name English
PIMOZIDE [VANDF]
Common Name English
R-6238
Code English
PIMOZIDE [USP-RS]
Common Name English
R-623
Code English
Classification Tree Code System Code
NCI_THESAURUS C29710
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
LIVERTOX NBK548846
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
WHO-ATC N05AG02
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
NDF-RT N0000180182
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
WHO-VATC QN05AG02
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
Code System Code Type Description
MERCK INDEX
m8816
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
PRIMARY Merck Index
LACTMED
Pimozide
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
PRIMARY
NCI_THESAURUS
C47672
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
PRIMARY
DAILYMED
1HIZ4DL86F
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
PRIMARY
DRUG CENTRAL
2172
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
PRIMARY
IUPHAR
90
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
PRIMARY
MESH
D010868
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
PRIMARY
RXCUI
8331
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
PRIMARY RxNorm
DRUG BANK
DB01100
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
PRIMARY
PUBCHEM
16362
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
PRIMARY
NSC
170984
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
PRIMARY
CHEBI
8212
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
PRIMARY
EPA CompTox
DTXSID8023474
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
PRIMARY
EVMPD
SUB09847MIG
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
PRIMARY
ECHA (EC/EINECS)
218-171-7
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
PRIMARY
RS_ITEM_NUM
1539508
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
PRIMARY
WIKIPEDIA
PIMOZIDE
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
PRIMARY
SMS_ID
100000081975
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
PRIMARY
CAS
2062-78-4
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
PRIMARY
FDA UNII
1HIZ4DL86F
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
PRIMARY
INN
2330
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
PRIMARY
ChEMBL
CHEMBL1423
Created by admin on Sat Dec 16 17:29:48 UTC 2023 , Edited by admin on Sat Dec 16 17:29:48 UTC 2023
PRIMARY
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Structure of PIMOZIDE
BASIS OF STRENGTH->SUBSTANCE
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D(4) DOPAMINE RECEPTOR
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D(2) DOPAMINE RECEPTOR
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Structure of PIMOZIDE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (TITRATION)
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5-HYDROXYTRYPTAMINE RECEPTOR 7
TARGET -> INHIBITOR
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This metabolism is catalyzed mainly by the cytochrome P450 3A4 (CYP 3A4) enzymatic system and to a lesser extent, by cytochrome P450 1A2 (CYP 1A2) and cytochrome P450 2D6 (CYP 2D6)
MAJOR
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Structure of 1-(1-(4,4-BIS(4-FLUOROPHENYL)BUTYL)-1,2,3,6-TETRAHYDROPYRIDIN-4-YL)-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE
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Structure of 4-DESFLUORO-2-FLUORO PIMOZIDE
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Related Record Type Details
Structure of PIMOZIDE
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