AMONAFIDE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H17N3O2
Molecular Weight	283.3251
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of AMONAFIDE

Structure Search

SMILES

CN(C)CCN1C(=O)C2=CC(N)=CC3=CC=CC(C1=O)=C23

InChI

InChIKey=UPALIKSFLSVKIS-UHFFFAOYSA-N

InChI=1S/C16H17N3O2/c1-18(2)6-7-19-15(20)12-5-3-4-10-8-11(17)9-13(14(10)12)16(19)21/h3-5,8-9H,6-7,17H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C16H17N3O2
Molecular Weight	283.3251
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:02:08 UTC 2023` Edited by `admin` on `Fri Dec 15 15:02:08 UTC 2023`
Record UNII	1Q8D39N37L
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

AMONAFIDE

Official Name

English

amonafide [INN]

Common Name

English

3-AMINO-N-(2-(DIMETHYLAMINO)ETHYL)NAPHTHALIMIDE

Common Name

English

NAFIDIMIDE

Common Name

English

AMONAFIDE [USAN]

Common Name

English

AS-1413

Code

English

1H-BENZ(DE)ISOQUINOLINE-1,3(2H)-DIONE, 5-AMINO-2-(2-(DIMETHYLAMINO)ETHYL)-

Systematic Name

English

AMONAFIDE [MART.]

Common Name

English

NSC-308847

Code

English

Amonafide [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C582

Created by admin on Fri Dec 15 15:02:08 UTC 2023 , Edited by admin on Fri Dec 15 15:02:08 UTC 2023

NCI_THESAURUS

C1968

Created by admin on Fri Dec 15 15:02:08 UTC 2023 , Edited by admin on Fri Dec 15 15:02:08 UTC 2023

Code System Code Type Description

RXCUI

1440270

Created by admin on Fri Dec 15 15:02:08 UTC 2023 , Edited by admin on Fri Dec 15 15:02:08 UTC 2023

PRIMARY

RxNorm

USAN

YY-6

Created by admin on Fri Dec 15 15:02:08 UTC 2023 , Edited by admin on Fri Dec 15 15:02:08 UTC 2023

PRIMARY

EPA CompTox

DTXSID30219562

Created by admin on Fri Dec 15 15:02:08 UTC 2023 , Edited by admin on Fri Dec 15 15:02:08 UTC 2023

PRIMARY

CAS

69408-81-7

Created by admin on Fri Dec 15 15:02:08 UTC 2023 , Edited by admin on Fri Dec 15 15:02:08 UTC 2023

PRIMARY

NSC

308847

Created by admin on Fri Dec 15 15:02:08 UTC 2023 , Edited by admin on Fri Dec 15 15:02:08 UTC 2023

PRIMARY

FDA UNII

1Q8D39N37L

Created by admin on Fri Dec 15 15:02:08 UTC 2023 , Edited by admin on Fri Dec 15 15:02:08 UTC 2023

PRIMARY

SMS_ID

100000087427

Created by admin on Fri Dec 15 15:02:08 UTC 2023 , Edited by admin on Fri Dec 15 15:02:08 UTC 2023

PRIMARY

DRUG BANK

DB05022

Created by admin on Fri Dec 15 15:02:08 UTC 2023 , Edited by admin on Fri Dec 15 15:02:08 UTC 2023

PRIMARY

ChEMBL

CHEMBL428676

Created by admin on Fri Dec 15 15:02:08 UTC 2023 , Edited by admin on Fri Dec 15 15:02:08 UTC 2023

PRIMARY

INN

5652

Created by admin on Fri Dec 15 15:02:08 UTC 2023 , Edited by admin on Fri Dec 15 15:02:08 UTC 2023

PRIMARY

NCI_THESAURUS

C71628

Created by admin on Fri Dec 15 15:02:08 UTC 2023 , Edited by admin on Fri Dec 15 15:02:08 UTC 2023

PRIMARY

MESH

C037020

Created by admin on Fri Dec 15 15:02:08 UTC 2023 , Edited by admin on Fri Dec 15 15:02:08 UTC 2023

PRIMARY

EVMPD

SUB05473MIG

Created by admin on Fri Dec 15 15:02:08 UTC 2023 , Edited by admin on Fri Dec 15 15:02:08 UTC 2023

PRIMARY

WIKIPEDIA

Amonafide

Created by admin on Fri Dec 15 15:02:08 UTC 2023 , Edited by admin on Fri Dec 15 15:02:08 UTC 2023

PRIMARY

PUBCHEM

50515

Created by admin on Fri Dec 15 15:02:08 UTC 2023 , Edited by admin on Fri Dec 15 15:02:08 UTC 2023

PRIMARY

Related Record Type Details


					LI06Q37TEG

AMONAFIDE L-MALATE

SALT/SOLVATE -> PARENT


					L5GTM43M4I

DNA TOPOISOMERASE 2-ALPHA

TARGET -> INHIBITOR


					2UAV344O66

AMONAFIDE DIHYDROCHLORIDE

SALT/SOLVATE -> PARENT

Related Record Type Details


					4TE48Q3W2E

N-ACETYLAMONAFIDE

METABOLITE -> PARENT

Qualification:

URINE


					9KVD6C9DPU

ACETAMIDE, N-(2,3-DIHYDRO-2-(2-(METHYLAMINO)ETHYL)-1,3-DIOXO-1H-BENZ(DE)ISOQUINOLIN-5-YL)-

METABOLITE -> PARENT

Qualification:

URINE


					BLW3994NJN

1H-BENZ(DE)ISOQUINOLINE-1,3(2H)-DIONE, 5-AMINO-2-(2-(DIMETHYLAMINO)ETHYL)-, N-OXIDE

METABOLITE -> PARENT

Qualification:

URINE

Related Record Type Details


					1Q8D39N37L

AMONAFIDE

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC

Volume of Distribution	PHARMACOKINETIC