U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Tue Apr 01 16:40:56 GMT 2025
Edited
by admin
on Tue Apr 01 16:40:56 GMT 2025
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type DUAL VARIABLE DOMAIN
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
1V8WRH3RVX
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
REMTOLUMAB
INN   WHO-DD  
INN  
Official Name English
A-1230717
Preferred Name English
remtolumab [INN]
Common Name English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS IL17A (INTERLEUKIN 17A, IL-17A) AND HOMO SAPIENS TNF (TUMOR NECROSIS FACTOR (TNF) SUPERFAMILY MEMBER 2, TNFSF2, TNF-ALPHA, TNFA)), HOMO SAPIENS MONOCLONAL ANTIBODY, TETRAVALENT BISPECIFIC GAMMA1 HEAVY CHAIN (1-
Systematic Name English
Remtolumab [WHO-DD]
Common Name English
ABT-122
Code English
IMMUNOGLOBULIN, ANTI-(TUMOR NECROSIS FACTOR .ALPHA./INTERLEUKIN 17) (SYNTHETIC HUMAN A-1230717 HEAVY CHAIN), DISULFIDE WITH SYNTHETIC HUMAN A-1230717 LIGHT CHAIN, DIMER
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C20401
Created by admin on Tue Apr 01 16:40:56 GMT 2025 , Edited by admin on Tue Apr 01 16:40:56 GMT 2025
NCI_THESAURUS C1454
Created by admin on Tue Apr 01 16:40:56 GMT 2025 , Edited by admin on Tue Apr 01 16:40:56 GMT 2025
Code System Code Type Description
INN
10345
Created by admin on Tue Apr 01 16:40:56 GMT 2025 , Edited by admin on Tue Apr 01 16:40:56 GMT 2025
PRIMARY
NCI_THESAURUS
C152189
Created by admin on Tue Apr 01 16:40:56 GMT 2025 , Edited by admin on Tue Apr 01 16:40:56 GMT 2025
PRIMARY
SMS_ID
100000173003
Created by admin on Tue Apr 01 16:40:56 GMT 2025 , Edited by admin on Tue Apr 01 16:40:56 GMT 2025
PRIMARY
CAS
1791410-27-9
Created by admin on Tue Apr 01 16:40:56 GMT 2025 , Edited by admin on Tue Apr 01 16:40:56 GMT 2025
PRIMARY
DRUG BANK
DB15128
Created by admin on Tue Apr 01 16:40:56 GMT 2025 , Edited by admin on Tue Apr 01 16:40:56 GMT 2025
PRIMARY
IUPHAR
9597
Created by admin on Tue Apr 01 16:40:56 GMT 2025 , Edited by admin on Tue Apr 01 16:40:56 GMT 2025
PRIMARY
FDA UNII
1V8WRH3RVX
Created by admin on Tue Apr 01 16:40:56 GMT 2025 , Edited by admin on Tue Apr 01 16:40:56 GMT 2025
PRIMARY
From To
1_22 1_96
1_153 1_227
1_284 1_340
1_401 1_461
1_507 1_565
2_22 2_96
2_153 2_227
2_284 2_340
2_401 2_461
2_507 2_565
3_23 3_88
3_140 3_205
3_251 3_311
4_23 4_88
4_140 4_205
4_251 4_311
1_360 3_331
2_360 4_331
1_366 2_366
1_369 2_369
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_437
N 2_437
Related Record Type Details
TUMOR NECROSIS FACTOR-.ALPHA. HUMAN (PLASMA DERIVED, SOLUBLE FORM)
TARGET -> INHIBITOR
INTERLEUKIN-17A
TARGET -> INHIBITOR
Related Record Type Details
REMTOLUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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