Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C10H8 |
| Molecular Weight | 128.1705 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C1=CC2=CC=CC=C2C=C1
InChI
InChIKey=UFWIBTONFRDIAS-UHFFFAOYSA-N
InChI=1S/C10H8/c1-2-6-10-8-4-3-7-9(10)5-1/h1-8H
| Molecular Formula | C10H8 |
| Molecular Weight | 128.1705 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
DescriptionCurator's Comment: description was created based on several sources, including:
DOI: 10.1007/978-0-387-30160-0_7643
http://npic.orst.edu/factsheets/naphgen.html
http://www.cdc.gov/niosh/npg/npgd0439.html
Curator's Comment: description was created based on several sources, including:
DOI: 10.1007/978-0-387-30160-0_7643
http://npic.orst.edu/factsheets/naphgen.html
http://www.cdc.gov/niosh/npg/npgd0439.html
Naphthalene is a crystalline aromatic hydrocarbon usually obtained by distillation of coal tar. Once used as a moth repellent, it is now important as a reactant in the production of phthalic anhydride, which in turn is used for making plasticizers, alkyd resins, and polyester resins. Other fumigant uses of naphthalene include use in soil as a fumigant pesticide, and in attic spaces to repel animals. In the past, naphthalene was administered orally to kill parasitic worms in livestock. In humans, exposure to large amounts of naphthalene may damage or destroy red blood cells. Humans, particularly children, have developed this condition after ingesting mothballs or deodorant blocks containing naphthalene. Some of the symptoms of naphthalene poisoning are fatigue, lack of appetite, restlessness, and pale skin. Exposure to large amounts of naphthalene may also cause nausea, vomiting, diarrhea, blood in the urine, and jaundice (yellow coloration of the skin).
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: map00980 Sources: https://www.ncbi.nlm.nih.gov/pubmed/8240407 |
|||
Target ID: GO:0030330 Sources: https://www.ncbi.nlm.nih.gov/pubmed/10802220 |
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Target ID: GO:0034440 Sources: https://www.ncbi.nlm.nih.gov/pubmed/10802220 |
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Primary | EQUIOPATHICS WRM CLEAR Approved UseIndicated for the treatment of worm infestations |
|||
| Palliative | ALLERGIES Approved UseUses for relief of allergy symptoms affecting the mucous membranes and skin |
|||
| Palliative | NAPHTHALINUM Approved UseNaphtalinum helps in coryza and hay fever. |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Use of selective inhibitors and chromogenic substrates to differentiate bacteria based on toluene oxygenase activity. | 2001-09 |
|
| Efficient polycyclic aromatic hydrocarbons dihydroxylation in direct micellar systems. | 2001-08-05 |
|
| Solid-state structures of group 1 and group 2 metal 1,5-naphthalenedisulfonates: systematic investigation of lamellar three-dimensional networks constructed by metal arenedisulfonate. | 2001-08 |
|
| Mutagenicity of electrophilic N-acyloxy-N-alkoxyamides. | 2001-07-25 |
|
| Active site characteristics of CYP4B1 probed with aromatic ligands. | 2001-07-24 |
|
| Highly potent growth hormone secretagogues: hybrids of NN703 and ipamorelin. | 2001-07-23 |
|
| Corannulene as a Lewis base: computational modeling of protonation and lithium cation binding. | 2001-07-11 |
|
| Marinobacter strain NCE312 has a Pseudomonas-like naphthalene dioxygenase. | 2001-07-10 |
|
| Biodegradation of non-desorbable naphthalene in soils. | 2001-07-01 |
|
| Synthesis and in vitro antifungal activity of 1-amino-3,4-dialkylnaphthalene-2-carbonitriles and their analogues. | 2001-07 |
|
| No enhancement in bioconcentration of organic contaminants by low levels of DOM. | 2001-07 |
|
| Arylisothiocyanate-containing esters of caffeic acid designed as affinity ligands for HIV-1 integrase. | 2001-07 |
|
| Effectiveness of an anaerobic granular activated carbon fluidized-bed bioreactor to treat soil wash fluids: a proposed strategy for remediating PCP/PAH contaminated soils. | 2001-07 |
|
| Biodegradation of carbaryl by a Micrococcus species. | 2001-07 |
|
| Enhancing reductive cleavage of aromatic carboxamides. | 2001-06-28 |
|
| Determination of trace levels of manganese in various biological and environmental samples by atomic absorption spectrometry after solid-liquid extraction and preconcentration with the ion pair formed by the nitroso-S anion and the tetradecyldimethylbenzylammonium cation. | 2001-06-22 |
|
| A P450 BM-3 mutant hydroxylates alkanes, cycloalkanes, arenes and heteroarenes. | 2001-06-15 |
|
| Characterization of volatile organic compounds in smoke at experimental fires. | 2001-06-08 |
|
| 2-Amino-6-arylsulfonylbenzonitriles as non-nucleoside reverse transcriptase inhibitors of HIV-1. | 2001-06-07 |
|
| Removal of naphthalene, phenanthrene, and pyrene by sorbents from hot gas. | 2001-06-01 |
|
| Inhaled naphthalene causes dose dependent Clara cell cytotoxicity in mice but not in rats. | 2001-06-01 |
|
| Determination of absolute configuration using vibrational circular dichroism spectroscopy: the chiral sulfoxide 1-(2-methylnaphthyl) methyl sulfoxide. | 2001-06-01 |
|
| Determination of the electron affinities of alpha- and beta-naphthyl radicals using the kinetic method with full entropy analysis. The C-H bond dissociation energies of naphthalene. | 2001-06 |
|
| Synthesis of potential aldose reductase inhibitors based on minimal pharmacophore requirements. | 2001-06 |
|
| Clara cell secretory protein-expressing cells of the airway neuroepithelial body microenvironment include a label-retaining subset and are critical for epithelial renewal after progenitor cell depletion. | 2001-06 |
|
| Toxicity tests to assess pollutants removal during wastewater treatment and the quality of receiving waters in Argentina. | 2001-06 |
|
| Structure activity studies of the melanocortin-4 receptor by in vitro mutagenesis: identification of agouti-related protein (AGRP), melanocortin agonist and synthetic peptide antagonist interaction determinants. | 2001-05-22 |
|
| Convergent synthesis of potent peptide inhibitors of the Grb2-SH2 domain by palladium catalyzed coupling of a terminal alkyne. | 2001-05-07 |
|
| Mass/heat transfer in dimpled two-pass coolant passages with rotation. | 2001-05 |
|
| Determination of photophysical rate constants for the non-protected fluid room temperature phosphorescence of several naphthalene derivatives. | 2001-05 |
|
| Efficiency of naphthalene and salicylate degradation by a recombinant Pseudomonas putida mutant strain defective in glucose metabolism. | 2001-05 |
|
| High-rate 3-methylcatechol production in Pseudomonas putida strains by means of a novel expression system. | 2001-05 |
|
| Ambient air quality at the site of a former manufactured gas plant. | 2001-05 |
|
| Constitutive and inducible hydroxylase activities involved in the degradation of naphthalene by Cunninghamella elegans. | 2001-05 |
|
| Two new chlorinated naphthalene glycosides from Rumex patientia. | 2001-05 |
|
| Photochemistry of 2-hydroxy-4-trifluoromethylbenzoic acid, major metabolite of the photosensitizing platelet antiaggregant drug triflusal. | 2001-05 |
|
| Complete prediction of the 1H NMR spectrum of organic molecules by DFT calculations of chemical shifts and spin-spin coupling constants. | 2001-04-17 |
|
| Development of new urea-functionalized silica stationary phases. Characterization and chromatographic performance. | 2001-04-13 |
|
| Synthesis and pharmacology of site specific cocaine abuse treatment agents: a new synthetic methodology for methylphenidate analogs based on the Blaise reaction. | 2001-04 |
|
| A comparative study on the inhibition of human and bacterial kynureninase by novel bicyclic kynurenine analogues. | 2001-04 |
|
| Occurrence and potential adverse effects of semivolatile organic compounds in streambed sediment, United States, 1992-1995. | 2001-04 |
|
| Numerical simulation of the infrared emission of interstellar dust. | 2001-03-15 |
|
| Polycyclic aromatic hydrocarbons (PAHs) in indoor and outdoor air of Hangzhou, China. | 2001-03-01 |
|
| The Aspergillus nidulans pyrG89 mutation alters glycosylation of secreted acid phosphatase. | 2001-03 |
|
| Steric and electronic ligand perturbations in catalysis: asymmetric allylic substitution reactions using C2-symmetrical phosphorus-chiral (bi)ferrocenyl donors. | 2001-02-09 |
|
| DDT, PAH and PCB in sediments from the intertidal zone of the Bohai Sea and the Yellow Sea. | 2001-02 |
|
| Uptake of polycyclic aromatic hydrocarbon compounds by the gills of the bivalve mollusk Elliptio complanata. | 2001-02 |
|
| Oxidative coupling of O-silyl and O-alkyl enethers: application of the novel annulation sequence to the synthesis of fluorinated naphthaldehydes and naphthyl ketones. | 2001-01-26 |
|
| [The toxicity variation of organic extracts in drinking water treatment processes]. | 2001-01 |
|
| Hydrocarbon deposition and soil microflora as affected by highway traffic. | 2001 |
| Substance Class |
Chemical
Created
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admin
on
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Mon Mar 31 18:41:25 GMT 2025
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Mon Mar 31 18:41:25 GMT 2025
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| Record UNII |
2166IN72UN
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| Record Status |
Validated (UNII)
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NCI_THESAURUS |
C45188
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EPA PESTICIDE CODE |
55801
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2166IN72UN
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DTXSID8020913
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2166IN72UN
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SUB128902
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C29839
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184
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m7725
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37565
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931
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16482
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1311149
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1457083
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91-20-3
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NAPHTHALENE
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202-049-5
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C031721
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naphthalene
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100000174863
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